Treatment of diabetic ulcers, using autologous platelet and fibrinic gel. Experience the FIBRINET® device

Abstract There is evidence that platelets may be used locally as a source of growth factors that play a fundamental role in wound healing. From October 2008 to September 2009, at Tor Vergata Rome University Hospital, seven patients were enrolled in the study. All of these patients had ulcers with a...

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Bibliographic Details
Published in:Transfusion and apheresis science 2010-10, Vol.43 (2), p.171-172
Main Author: Marinacci, M
Format: Article
Language:English
Subjects:
Aged
Blood Platelets - cytology
Blood Pressure
Diabetic Foot - diagnosis
Diabetic Foot - pathology
Equipment and Supplies
Equipment Design
Female
Fibrin - chemistry
Flow Cytometry - methods
Health technology assessment
Hematology, Oncology and Palliative Medicine
Humans
Male
Middle Aged
Platelet Activation
Wound Healing
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Summary:Abstract There is evidence that platelets may be used locally as a source of growth factors that play a fundamental role in wound healing. From October 2008 to September 2009, at Tor Vergata Rome University Hospital, seven patients were enrolled in the study. All of these patients had ulcers with a extension over 3.5 cm2. Four patients achieved a total recovery of the ulcers, while three experienced a reduction of the diameter of the ulcers. Our data are preliminary, but it is possible to suggest that recovery of the ulcers using the FIBRINET® system is related to platelet activation in the specific ulcer area.
ISSN:1473-0502
1878-1683
DOI:10.1016/j.transci.2010.07.013