Felty's syndrome: When is splenectomy indicated?

The spectrum of disease was assessed in 43 patients with Felty's syndrome. Twenty-three underwent splenectomy. Although complete remission of neutropenia occurred in only two nonoperated patients, most of the patients had no serious infections during the subsequent period of observation. Operat...

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Bibliographic Details
Published in:	The American journal of surgery 1985-01, Vol.149 (2), p.272-275
Main Author:	Coon, William W.
Format:	Article
Language:	eng
Subjects:	Adult Aged Biological and medical sciences Diseases of the osteoarticular system Felty Syndrome - physiopathology Felty Syndrome - surgery Felty Syndrome - therapy Female Follow-Up Studies Humans Inflammatory joint diseases Leukocyte Count Lymphocytes Male Medical sciences Middle Aged Neutrophils Organ Size Splenectomy
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Summary:	The spectrum of disease was assessed in 43 patients with Felty's syndrome. Twenty-three underwent splenectomy. Although complete remission of neutropenia occurred in only two nonoperated patients, most of the patients had no serious infections during the subsequent period of observation. Operative morbidity was minimal in the splenectomized patients. On the basis of natural history of this condition, splenectomy should probably be restricted to neutropenic patients with serious or recurrent infections, patients with severe anemia requiring transfusions, those with the rare circumstance of profound thrombocytopenia, and those with non-healing leg ulcers.
ISSN:	0002-9610 1879-1883