Comparison of clinical information gained from routine blood-gas analysis and from gastric tonometry for intramural pH

The measurement of gastric intramucosal pH (pH i) has been advocated to assist in decision-making for critically ill patients. To assess whether the information obtained from the measurement of pH i can be obtained from other measurements of metabolic acidosis, we studied 20 consecutive patients adm...

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Bibliographic Details
Published in:The Lancet (British edition) 1993-01, Vol.341 (8838), p.142-146
Main Authors: Boyd, O., Mackay, C.J., Lamb, G., Grounds, R.M., Bennett, E.D., Bland, J.M.
Format: Article
Language:English
Subjects:
Acidosis - diagnosis
Adolescent
Adult
Aged
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Blood
Blood Gas Analysis
Digestive system
Emergency and intensive care: metabolism and nutrition disorders. Enteral and parenteral nutrition
Female
Gastric Acidity Determination
Humans
Hydrogen-Ion Concentration
Intensive care medicine
Male
Medical research
Medical sciences
Middle Aged
Weights & measures
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Summary:The measurement of gastric intramucosal pH (pH i) has been advocated to assist in decision-making for critically ill patients. To assess whether the information obtained from the measurement of pH i can be obtained from other measurements of metabolic acidosis, we studied 20 consecutive patients admitted to the intensive care unit. A mean of eight (range two to fourteen) data sets per patient were obtained, comprising measurement of arterial pH, pO 2, pCO 2, and oxygen saturation, tonometer balloon fluid pCO 2, arterial pressures, and cardiac output. Bicarbonate concentration, base deficit or excess in blood and extracellular fluid, and pH i were calculated from these measurements. Relations between the variables and pH i were assessed by within-subject correlation comparisons. There were significant correlations ( r>0·6, p
ISSN:0140-6736
1474-547X
DOI:10.1016/0140-6736(93)90005-2