Beneficial effect of epilepsy surgery in a case of childhood non-paraneoplastic limbic encephalitis

Summary This 15-year-old girl had subacute onset of secondary generalized seizures, confusion, and subsequent memory decline. MRI showed bilateral hippocampal swelling progressing to unilateral mesial temporal sclerosis (MTS) within 12 months. Epilepsy surgery was performed, and laboratory data were...

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Bibliographic Details
Published in:Epilepsy research 2010-08, Vol.90 (3), p.295-299
Main Authors: Muehlebner, Angelika, Groeppel, Gudrun, Pahs, Gerald, Hainfellner, Johannes A, Prayer, Daniela, Czech, Thomas, Feucht, Martha
Format: Article
Language:English
Subjects:
Adolescent
Anticonvulsants. Antiepileptics. Antiparkinson agents
Biological and medical sciences
Drug-resistance
Epilepsy surgery
Female
Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy
Hippocampus - pathology
Hippocampus - surgery
Humans
Limbic encephalitis
Limbic Encephalitis - complications
Limbic Encephalitis - pathology
Limbic Encephalitis - surgery
Magnetic Resonance Imaging
Medical sciences
Mesial temporal lobe epilepsy
Nervous system (semeiology, syndromes)
Neurology
Neuropharmacology
Pharmacology. Drug treatments
Sclerosis - complications
Sclerosis - pathology
Sclerosis - surgery
Seizures - etiology
Seizures - pathology
Seizures - surgery
Treatment Outcome
Unilateral hippocampal sclerosis
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Summary:Summary This 15-year-old girl had subacute onset of secondary generalized seizures, confusion, and subsequent memory decline. MRI showed bilateral hippocampal swelling progressing to unilateral mesial temporal sclerosis (MTS) within 12 months. Epilepsy surgery was performed, and laboratory data were consistent with non-paraneoplastic limbic encephalitis. 18 months after epilepsy surgery, the patient is seizure-free with stable cognitive functions.
ISSN:0920-1211
1872-6844
DOI:10.1016/j.eplepsyres.2010.05.009