Primary Nocardia farcinica brain abscess with secondary meningitis and ventriculitis in an immunocompetent patient, successfully treated with moxifloxacin

Summary We report a rare case of Nocardia farcinica occipital brain abscess in an immunocompetent patient with no underlying risk factors successfully treated with the antibiotic moxifloxacin. The patient underwent craniotomy and abscess drainage. Initial post-operative treatment with co-trimoxazole...

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Bibliographic Details
Published in:Acta neurochirurgica 2008-05, Vol.150 (5), p.505-506
Main Authors: Kandasamy, J., Iqbal, H. J., Cooke, R. P. D., Eldridge, P. R.
Format: Article
Language:English
Subjects:
Adult
Anti-Infective Agents - therapeutic use
Aza Compounds - therapeutic use
Brain Abscess - microbiology
Brain Abscess - surgery
Brief Report of Special Case
Cerebral Ventricles - microbiology
Drainage
Encephalitis - microbiology
Fluoroquinolones
Humans
Immunocompetence
Interventional Radiology
Male
Medicine
Medicine & Public Health
Meningitis, Bacterial - microbiology
Minimally Invasive Surgery
Neurology
Neuroradiology
Neurosurgery
Neurosurgical Procedures
Nocardia farcinica
Nocardia Infections - complications
Nocardia Infections - drug therapy
Occipital Lobe - microbiology
Postoperative Care
Quinolines - therapeutic use
Skull Base - microbiology
Surgical Orthopedics
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Summary:Summary We report a rare case of Nocardia farcinica occipital brain abscess in an immunocompetent patient with no underlying risk factors successfully treated with the antibiotic moxifloxacin. The patient underwent craniotomy and abscess drainage. Initial post-operative treatment with co-trimoxazole produced a limited response. Despite the development of skull base meningitis and ventriculitis subsequent addition of moxifloxacin produced an excellent outcome.
ISSN:0001-6268
0942-0940
DOI:10.1007/s00701-008-1578-x