TAL effectors: finding plant genes for disease and defense

TAL effectors: finding plant genes for disease and defense

Transcription activator like effectors (TALEs) are injected via the type III secretion pathway of many plant pathogenic Xanthomonas spp. into plant cells where they contribute to disease or trigger resistance by binding to DNA and turning on TALE-specific host genes. Advances in our understanding of...

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Bibliographic Details
Published in:Current opinion in plant biology 2010-08, Vol.13 (4), p.394-401
Main Authors: Bogdanove, Adam J, Schornack, Sebastian, Lahaye, Thomas
Format: Article
Language:eng
Subjects:
adaptation
bacterial colonization
bacterial diseases of plants
bacterial proteins
biochemical pathways
defense mechanisms
disease resistance
DNA, Plant - metabolism
DNA-binding domains
genes
Genes, Plant
host plants
host-pathogen relationships
immune response
immunity
immunosuppression (physiological)
literature reviews
microbial genetics
pathogenesis
Plant Diseases - genetics
Plant Diseases - prevention & control
plant genetics
transcription factors
Transcriptional Activation
Xanthomonas
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Summary:Transcription activator like effectors (TALEs) are injected via the type III secretion pathway of many plant pathogenic Xanthomonas spp. into plant cells where they contribute to disease or trigger resistance by binding to DNA and turning on TALE-specific host genes. Advances in our understanding of TALEs and their targets have yielded new models for pathogen recognition and defense. Similarly, we have gained insight into plant molecules and processes that can be co-opted to promote infection. Recent elucidation of the basis for specificity in DNA binding by TALEs expedites further discovery and opens the door to biotechnological applications. This article reviews the most significant findings in TALE research, with a focus on recent advances, and discusses future prospects including pressing questions yet to be answered.
ISSN:1369-5266
1879-0356