Synthesis of water-soluble polyimidoamines for biomedical application. II. Polymers possessing intrachain-type secondary amino groups suitable for side-chain attachment

A part of a program to synthesize water-soluble polymeric carriers suitable for drug binding, the polyaddition reaction of methylenebisacrylamide with comonomers containing two primary amino groups is investigated. The copolymerization of the bisacrylamide with equimolar quantities off primary diami...

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Bibliographic Details
Published in:Journal of applied polymer science 1993-01, Vol.50 (3), p.393-401
Main Authors: Caldwell, Gregg, Neuse, Eberhard W, Stephanou, Andreas
Format: Article
Language:English
Online Access:Get full text
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Summary:A part of a program to synthesize water-soluble polymeric carriers suitable for drug binding, the polyaddition reaction of methylenebisacrylamide with comonomers containing two primary amino groups is investigated. The copolymerization of the bisacrylamide with equimolar quantities off primary diamines under properly controlled experimental conditions is found to proceed in a linear propagation, giving rise to the formation of polyamides comprising two or more secondary amino groups in the recurring unit.
ISSN:0021-8995