Toxicological and nutraceutical assessments of peanut sprouts as daily supplements to feed Sprague-Dawley rats for 18 weeks

BACKGROUND: Peanut sprouts are occasionally consumed by peanut farmers. To investigate the possibility of introducing peanut sprouts as a functional vegetable to the public, an in vivo experiment involving toxicological and nutraceutical assessments was conducted.RESULTS: Sixty female Sprague-Dawley...

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Bibliographic Details
Published in:Journal of the science of food and agriculture 2008-09, Vol.88 (12), p.2201-2207
Main Authors: Lin, Bo-Si, Lien, Tu-Fa, Chao, Mao-Rong, Lai, Tzu-Yuan, Chang, Ju-Chun, Chou, Shieh-Jen, Liao, Hui-Fen, Chiou, Robin Y.Y
Format: Article
Language:English
Subjects:
aflatoxin
Arachis hypogaea
Biological and medical sciences
blood chemistry
blood lipids
body weight
Dietary supplements
Feed and pet food industries
Food industries
Food toxicology
functional foods
Fundamental and applied biological sciences. Psychology
kidneys
lipemic effect
liver
nutraceutical
peanut
peanut sprout
Peanuts
rats
Rodents
spleen
Sprague-Dawley rat
sprouts (food)
Toxicity
toxicity testing
triacylglycerols
weight
weight gain
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Summary:BACKGROUND: Peanut sprouts are occasionally consumed by peanut farmers. To investigate the possibility of introducing peanut sprouts as a functional vegetable to the public, an in vivo experiment involving toxicological and nutraceutical assessments was conducted.RESULTS: Sixty female Sprague-Dawley rats (8 weeks old) were fed with peanut sprouts as a dietary supplement for 18 weeks. The rats were divided into five groups and fed with different daily supplements, namely 0 g (control), 16.5, 10 or 6 g of sprouts or 2.4 g of kernels. Aflatoxin contents of the sprouts (n = 24) were less than 1 μg kg⁻¹. Body weights of all rats increased with feeding time, and final body weights differed insignificantly among test groups (P > 0.05). Weights of liver, kidney and spleen and organ/body weight ratios varied insignificantly among test groups (P > 0.05). All serum and blood cell determinations differed insignificantly (P > 0.05) among test groups, apart from the observation of a significant lowering of serum triacylglycerol (TG) level in the 10 g sprout group (P < 0.05).CONCLUSION: In general, no obvious growth hazard or health toxicity was detected. For nutraceutical development, the lowering of serum TG level achieved by appropriate intake of peanut sprouts is noteworthy. Copyright
ISSN:0022-5142
1097-0010
DOI:10.1002/jsfa.3335