TYPE OF DIAMINOPIMELIC ACID DIFFERENT IN AERIAL AND VEGETATIVE MYCELIA OF SETAMYCIN-PRODUCING ACTINOMYCETE KM-6054

Strain KM-6054, an Actinomycete strain isolated from a soil sample collected at Setagayaku, Tokyo, has been reported to produce a new antibiotic, setamycin, showing activity against some fungi, trichomonads and Gram-positive bacteria. In the course of taxonomic study, the authors found that the myce...

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Bibliographic Details
Published in:Journal of antibiotics 1981, Vol.34(12), pp.1633-1634
Main Authors: OMURA, SATOSHI, IWAI, YUZURU, TAKAHASHI, YOKO, KOJIMA, KAZUKO, OTOGURO, KAZUHIKO, OIWA, RUIKO
Format: Article
Language:English
Subjects:
Actinomycetales - analysis
Actinomycetales - classification
Actinomycetales - metabolism
Amino Acids, Diamino - analysis
Anti-Bacterial Agents - biosynthesis
Diaminopimelic Acid - analysis
Macrolides
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Summary:Strain KM-6054, an Actinomycete strain isolated from a soil sample collected at Setagayaku, Tokyo, has been reported to produce a new antibiotic, setamycin, showing activity against some fungi, trichomonads and Gram-positive bacteria. In the course of taxonomic study, the authors found that the mycelia of strain KM-6054 contains both LL-diaminopimelic acid (DAP) and its meso-isomer, although this strain may be thought to be a strain of genus Streptomyces from the morphology, cultural characteristics, etc. It was also found that when DAP analysis was carried out separately on aerial and vegetative mycelia grown on an agar medium, most of DAP contained in aerial mycelia is LL-isomer while that in vegetative mycelia is meso-isomer. There is no report concerning Actinomycete strains which exhibit the above characteristics. The present communication deals with taxonomic properties of strain KM-6054.
ISSN:0021-8820
1881-1469
DOI:10.7164/antibiotics.34.1633