Preoperative mapping of cortical language areas in adult brain tumour patients using PET and individual non-normalised SPM analyses

In patients scheduled for the resection of perisylvian brain tumours, knowledge of the cortical topography of language functions is crucial in order to avoid neurological deficits. We investigated the applicability of statistical parametric mapping (SPM) without stereotactic normalisation for indivi...

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Published in:European journal of nuclear medicine and molecular imaging 2003-07, Vol.30 (7), p.951-960
Main Authors: MEYER, Philipp T, STURZ, Laszlo, SCHRECKENBERGER, Mathias, SPETZGER, Uwe, MEYER, Georg F, SETANI, Keyvan S, SABRI, Osama, BUELL, Udalrich
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Language:eng
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Summary:In patients scheduled for the resection of perisylvian brain tumours, knowledge of the cortical topography of language functions is crucial in order to avoid neurological deficits. We investigated the applicability of statistical parametric mapping (SPM) without stereotactic normalisation for individual preoperative language function brain mapping using positron emission tomography (PET). Seven right-handed adult patients with left-sided brain tumours (six frontal and one temporal) underwent 12 oxygen-15 labelled water PET scans during overt verb generation and rest. Individual activation maps were calculated for P
ISSN:1619-7070
1619-7089