The evolution of symptoms in the early course of non-affective psychosis

Most previous studies investigating the factor structure of psychosis have focussed on chronic samples. First episode samples with longitudinal follow up are few. To investigate the stability and validity of symptom factors, a sample of 257 patients with DSM IV nonaffective psychoses were assessed u...

Full description

Saved in:
Bibliographic Details
Published in:Schizophrenia research 2003-09, Vol.63 (1), p.171-179
Main Authors: Drake, Richard James, Dunn, Graham, Tarrier, Nick, Haddock, Gill, Haley, Cliff, Lewis, Shôn
Format: Article
Language:English
Subjects:
Acute Disease
Adult
Biological and medical sciences
Cognitive Therapy - methods
Disease Progression
Factor Analysis, Statistical
Female
Follow-Up Studies
Humans
Male
Medical sciences
Mood Disorders - diagnosis
PANSS
Psychology. Psychoanalysis. Psychiatry
Psychometrics. Diagnostic aid systems
Psychopathology. Psychiatry
Psychosis
Psychotic Disorders - diagnosis
Psychotic Disorders - psychology
Psychotic Disorders - therapy
Reproducibility of Results
Severity of Illness Index
Surveys and Questionnaires
Symptoms
Techniques and methods
Time Factors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Most previous studies investigating the factor structure of psychosis have focussed on chronic samples. First episode samples with longitudinal follow up are few. To investigate the stability and validity of symptom factors, a sample of 257 patients with DSM IV nonaffective psychoses were assessed using the PANSS during the acute first episode and at 3- and 18-month follow up. Exploratory factor analysis of the changes in PANSS item scores over time gave a five-factor solution. This was consistent with the solutions to factor analyses at the initial assessment and each of the follow-ups. However, there was progression over follow-up. Confirmatory factor analysis demonstrated that symptom ratings at 18-month follow-up fitted the models from existing research, in relatively chronic samples, better than the ratings at the initial assessment. A psychomotor poverty factor showed most stability over time and a positive symptom factor most change. Factors showed different associations with demographic and external variables, further supporting their validity.
ISSN:0920-9964
1573-2509
DOI:10.1016/S0920-9964(02)00334-1