Mortality and recovery after stroke in The Gambia

There are no previously published studies of the long-term outcome of stroke in sub-Saharan Africa. Our goal was to determine the case fatality, time to and cause of death, and recovery in a hospital cohort of stroke patients in The Gambia. For 1 year beginning April 1, 1990, any patient presenting...

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Bibliographic Details
Published in:Stroke (1970) 2003-07, Vol.34 (7), p.1604-1609
Main Authors: WALKER, Richard W, ROLFE, Michael, KELLY, Peter J, GEORGE, Melville O, JAMES, Oliver F. W
Format: Article
Language:English
Subjects:
Adult
Age Distribution
Aged
Aged, 80 and over
Biological and medical sciences
Cause of Death
Female
Follow-Up Studies
Gambia - epidemiology
Hospital Mortality
Humans
Male
Medical sciences
Middle Aged
Neurology
Prognosis
Proportional Hazards Models
Prospective Studies
Recovery of Function
Stroke - diagnosis
Stroke - mortality
Survival Rate
Vascular diseases and vascular malformations of the nervous system
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Summary:There are no previously published studies of the long-term outcome of stroke in sub-Saharan Africa. Our goal was to determine the case fatality, time to and cause of death, and recovery in a hospital cohort of stroke patients in The Gambia. For 1 year beginning April 1, 1990, any patient presenting to the Royal Victoria Hospital (Banjul) with a diagnosis of stroke or having a stroke as an inpatient was recruited. After a standardized assessment, patients were followed up at 1 month, 6 months, and 3 to 4 years to assess recovery or, for those who died, record the date and likely cause of death. Mean age of the 106 patients (70 men) was 58 years (range, 20 to 93 years). By 1 and 6 months, 29 (27%) and 47 (44%), respectively, had died, with only 27 (25%) surviving to final follow-up (4 patients not traced). Death occurred in hospital in 43 patients (57%). Cause of death was the initial stroke in 46 (61%), further stroke in 5 (7%), infection in 9 (12%), miscellaneous in 8 (11%) (only 1 vascular), and unknown in 7 (9%). On Cox regression analysis, incontinence in the first 24 hours, sensory inattention, and impaired gag reflex on admission were significant predictors of mortality. Predictors of recovery were similar to those of developed countries. Despite the young mean age, there was a high case fatality rate. The main cause of death was the stroke itself, and ischemic heart disease was very rare.
ISSN:0039-2499
1524-4628
DOI:10.1161/01.STR.0000077943.63718.67