Subjective Memory Deficits in People with and without Dementia: Findings from the 10/66 Dementia Research Group Pilot Studies in Low- and Middle-Income Countries

OBJECTIVES: To compare subjective memory deficit (SMD) in older adults with and without dementia or depression across multiple centers in low‐ and middle‐income countries (LAMICs). DESIGN: Secondary analysis of data from 23 case control studies. SETTING: Twenty‐three centers in India, Southeast Asia...

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Published in:Journal of the American Geriatrics Society (JAGS) 2009-11, Vol.57 (11), p.2118-2124
Main Author: 10/66 Dementia Research Group
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Alzheimer Disease - diagnosis
Alzheimer Disease - epidemiology
Biological and medical sciences
Comorbidity
Comparative studies
Cross-Cultural Comparison
Cross-Sectional Studies
Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
Dementia
depression
Depressive Disorder - diagnosis
Depressive Disorder - epidemiology
Developing Countries
Educational Status
elderly
Female
General aspects
Humans
Male
Mass Screening
Medical sciences
Memory
Memory Disorders - diagnosis
Memory Disorders - epidemiology
Mental depression
Mental Recall
Middle Aged
Miscellaneous
Neurology
Older people
Pilot Projects
Public health. Hygiene
Public health. Hygiene-occupational medicine
Socioeconomic Factors
subjective memory deficit
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Summary:OBJECTIVES: To compare subjective memory deficit (SMD) in older adults with and without dementia or depression across multiple centers in low‐ and middle‐income countries (LAMICs). DESIGN: Secondary analysis of data from 23 case control studies. SETTING: Twenty‐three centers in India, Southeast Asia (including China), Latin America and the Caribbean, Nigeria, and Russia. PARTICIPANTS: Two thousand six hundred ninety‐two community‐dwelling people aged 60 and older in one of three groups: people with dementia, people with depression, and controls free of dementia and depression. MEASUREMENTS: SMD was derived from the Geriatric Mental State examination. RESULTS: Median SMD frequency was lowest in participants without dementia (26.2%) and higher in those with depression (50.0%) and dementia (66.7%). Frequency of SMD varied between centers. Depression and dementia were consistently associated with SMD. Older age and hypochondriasis were associated with SMD only in subjects without dementia. In those with dementia, SMD was associated with better cognitive function, whereas the reverse was the case in controls. CONCLUSION: Associations with SMD may differ between subjects with and without dementia living in LAMICs.
ISSN:0002-8614
1532-5415
DOI:10.1111/j.1532-5415.2009.02523.x