Aerobic interval training versus continuous moderate exercise after coronary artery bypass surgery: A randomized study of cardiovascular effects and quality of life

Background Peak oxygen uptake (V o2peak ) strongly predicts mortality in cardiac patients. We compared the effects of aerobic interval training (AIT) versus moderate continuous training (MCT) on V o2peak and quality of life after coronary artery bypass grafting (CABG). Methods Fifty-nine CABG patien...

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Published in:The American heart journal 2009-12, Vol.158 (6), p.1031-1037
Main Authors: Moholdt, Trine T., MSc, Amundsen, Brage H., PhD, Rustad, Lene Annette, MD, Wahba, Alexander, PhD, Løvø, Kjersti T., PT, Gullikstad, Lisbeth R., PT, Bye, Anja, PhD, Skogvoll, Eirik, PhD, Wisløff, Ulrik, PhD, Slørdahl, Stig A., PhD
Format: Article
Language:English
Subjects:
Cardiology
Cardiovascular
Cardiovascular Physiological Phenomena
Cholesterol
Coronary Artery Bypass - rehabilitation
Coronary vessels
Exercise
Exercise - physiology
Female
Heart attacks
Humans
Male
Middle Aged
Quality of Life
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Summary:Background Peak oxygen uptake (V o2peak ) strongly predicts mortality in cardiac patients. We compared the effects of aerobic interval training (AIT) versus moderate continuous training (MCT) on V o2peak and quality of life after coronary artery bypass grafting (CABG). Methods Fifty-nine CABG patients were randomized to either AIT at 90% of maximum heart rate or MCT at 70% of maximum heart rate, 5 d/wk, for 4 weeks at a rehabilitation center. Primary outcome was V o2peak , at baseline, after rehabilitation (4 weeks), and after 6 months of home-based exercise (6 months). Results V o2peak increased between baseline and 4 weeks in AIT (27.1 ± 4.5 vs 30.4 ± 5.5 mL·kg−1 ·min−1 , P < .001) and MCT (26.2 ± 5.2 vs 28.5 ± 5.6 mL·kg−1 ·min−1 , P < .001; group difference, not significant). Aerobic interval training increased V o2peak between 4 weeks and 6 months (30.4 ± 5.5 vs 32.2 ± 7.0 mL·kg−1 ·min−1 , P < .001), with no significant change in MCT (28.5 ± 5.6 vs 29.5 ± 5.7 mL·kg−1 ·min−1 ). Quality of life improved in both groups from baseline to 4 weeks, remaining improved at 6 months. There were no changes in echocardiographic systolic and diastolic left ventricular function. Adiponectin increased between 4 weeks and 6 months in both groups (group differences, not significant). Conclusions Four weeks of intense training increased V o2peak significantly after both AIT and MCT. Six months later, the AIT group had a significantly higher V o2peak than MCT. The results indicate that AIT and MCT increase V o2peak similarly in the short term, but with better long-term effect of AIT after CABG.
ISSN:0002-8703
1097-6744
DOI:10.1016/j.ahj.2009.10.003