EUS in pediatric patients

Background The knowledge of EUS use in children is limited. Objective We investigated the indications, feasibility, safety, and clinical utility of EUS in the management of pediatric GI, pancreatobiliary, and mediastinal diseases. Design Retrospective study. Setting Two tertiary referral university...

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Bibliographic Details
Published in:	Gastrointestinal endoscopy 2009-11, Vol.70 (5), p.892-898
Main Authors:	Attila, Tan, MD, Adler, Douglas G., MD, Hilden, Kristen, MS, Faigel, Douglas O., MD
Format:	Article
Language:	eng
Subjects:	Adolescent Biliary Tract Diseases - diagnostic imaging Biological and medical sciences Biopsy, Fine-Needle - methods Child Child, Preschool Diagnosis, Differential Digestive system. Abdomen Endoscopy Endosonography - methods Endosonography - utilization Feasibility Studies Female Follow-Up Studies Gastroenterology and Hepatology Gastroenterology. Liver. Pancreas. Abdomen Gastrointestinal Diseases - diagnostic imaging Humans Investigative techniques, diagnostic techniques (general aspects) Male Mediastinal Diseases - diagnostic imaging Medical sciences Pancreatic Diseases - diagnostic imaging Reproducibility of Results Retrospective Studies
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Summary:	Background The knowledge of EUS use in children is limited. Objective We investigated the indications, feasibility, safety, and clinical utility of EUS in the management of pediatric GI, pancreatobiliary, and mediastinal diseases. Design Retrospective study. Setting Two tertiary referral university hospitals. Patients Consecutive children age younger than 18 years referred over a 7-year period for EUS evaluation. Results Forty EUS scans were performed in 38 children with a mean age of 13.5 years. The indications for pancreatobiliary endosonography were pancreatitis (n = 10), solid pancreatic mass (n = 7), cystic pancreatic mass (n = 1), cyst in the setting of chronic pancreatitis (n = 1), suspected annular pancreas (n = 1), celiac plexus block (n = 1), suspected common bile duct stone (n = 1), abdominal pain and atrophic pancreas (n = 1), ampullary adenoma (n = 1), and abnormal MRCP in a patient with jaundice (n = 1). The indications for gastric EUS were mucosal lesions (n = 2) and subepithelial lesions (n = 4). The indications for mediastinal endosonography were mediastinal masses/lymph nodes (n = 5). The remaining evaluations were performed for esophageal stricture (n = 1), unexplained abdominal pain (n = 1), unexplained abdominal pain with celiac axis block (n = 1), and perirectal fluid collection (n = 1). EUS-guided FNA (EUS-FNA) was performed in 12 (30%) cases and established the correct diagnosis in 9 (75%). EUS-guided fine-needle injections for celiac axis block were performed in 2 (5%) cases. The procedure was successful in all patients, and no complications related to sedation, EUS, or EUS-FNA were encountered. Limitation Retrospective study. Conclusion EUS and EUS-FNA are feasible and safe and have a significant impact on the management of pediatric GI, pancreatobiliary, and mediastinal diseases.
ISSN:	0016-5107 1097-6779