Chemical and antioxidant evaluation of Indian gooseberry (emblica officinalis gaertn., syn. phyllanthus emblica L.) supplements

Indian gooseberry (Emblica officinalis Gaertn.) (Euphorbiaceae) has a distinguished history in Ayurveda medicine and is ascribed a number of medicinal properties and as a dietary supplement, its use is increasing in Western countries. It is thought that its beneficial properties are a function of it...

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Bibliographic Details
Published in:Phytotherapy research 2009-09, Vol.23 (9), p.1309-1315
Main Authors: Poltanov, Eugeny A, Shikov, Alexander N, Dorman, H.J. Damien, Pozharitskaya, Olga N, Makarov, Valery G, Tikhonov, Vladimir P, Hiltunen, Raimo
Format: Article
Language:eng ; rus
Subjects:
antioxidant activity
Antioxidants - analysis
Antioxidants - chemistry
botanicals
Chromatography, High Pressure Liquid
composition
dietary supplements
Emblica officinalis
Flavonoids - analysis
Flavonoids - chemistry
Free Radical Scavengers - analysis
Free Radical Scavengers - chemistry
free radical scavenging
Fruit - chemistry
Iron Chelating Agents - analysis
Iron Chelating Agents - chemistry
Molecular Structure
Phenols - analysis
Phenols - chemistry
Phyllanthus emblica - chemistry
Plant Extracts - chemistry
Tannins - analysis
Tannins - chemistry
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Summary:Indian gooseberry (Emblica officinalis Gaertn.) (Euphorbiaceae) has a distinguished history in Ayurveda medicine and is ascribed a number of medicinal properties and as a dietary supplement, its use is increasing in Western countries. It is thought that its beneficial properties are a function of its antioxidant potency. The study investigated the chemistry and antioxidant properties of four commercial E. officinalis fruit extracts in order to determine if there are any qualitative-quantitative differences. All extracts produced positive responses in the total phenol, total flavonoid and total tannin assays. The presence of predominantly (poly)phenolic analytes, e.g. ellagic and gallic acids and corilagin, was confirmed by RP-HPLC coupled with photodiode array detection. Despite ascorbic acid being a major constituent of E. officinalis fruits, the furanolactone could not be identified in one of the samples. The extracts demonstrated varying degrees of antioxidative efficacy. The extract designated IG-3 was consistently amongst the most effective extracts in the iron(III) reduction and 1,1-diphenyl-2-picrylhydrazyl and superoxide anion radical scavenging assays while the extract designated IG-1 demonstrated the best hydroxyl radical scavenging activity. All extracts appeared to be incapable of chelating iron(II) at realistic concentrations. Copyright © 2009 John Wiley '' Sons, Ltd.
ISSN:0951-418X
1099-1573
DOI:10.1002/ptr.2775