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Bimatoprost 0.03% gel for cosmetic eyelash growth and enhancement
Summary Objective To evaluate a bimatoprost gel for enhancing eyelash growth, adverse effects, and change in intraocular pressure (IOP). Methods Prospective, double‐masked, randomized controlled study. Fifty‐two patients without ocular disease were assigned a control or bimatoprost 0.03% gel to ap...
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| Published in: | Journal of cosmetic dermatology 2010-06, Vol.9 (2), p.96-102 |
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| container_end_page | 102 |
| container_issue | 2 |
| container_start_page | 96 |
| container_title | Journal of cosmetic dermatology |
| container_volume | 9 |
| creator | Woodward, Julie A Haggerty, Chris J Stinnett, Sandra S Williams, Zinaria Y |
| description | Summary
Objective To evaluate a bimatoprost gel for enhancing eyelash growth, adverse effects, and change in intraocular pressure (IOP).
Methods Prospective, double‐masked, randomized controlled study. Fifty‐two patients without ocular disease were assigned a control or bimatoprost 0.03% gel to apply to the eyelid margin once a day.
Results The adjusted mean change in eyelash length from baseline to 6 months was 0.77 mm in the bimatoprost group and −0.12 mm in the control group (P = 0.004). Adverse effects were experienced by 2 of 16 patients (12.5%) in the control group and 9 of 36 patients (25%) in the bimatoprost gel group. Mean change in IOP from baseline to 6 months was 0.685 mmHg in the control group and −2.04 mmHg in the bimatoprost group (P = 0.009).
Conclusions Bimatoprost gel was effective in enhancing eyelash growth. The most common adverse effect for the bimatoprost gel was conjunctival and eyelid hyperemia, while the most severe was recurrent anterior uveitis. Mean IOP was reduced in subjects using the bimatoprost gel. |
| doi_str_mv | 10.1111/j.1473-2165.2010.00487.x |
| format | article |
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Objective To evaluate a bimatoprost gel for enhancing eyelash growth, adverse effects, and change in intraocular pressure (IOP).
Methods Prospective, double‐masked, randomized controlled study. Fifty‐two patients without ocular disease were assigned a control or bimatoprost 0.03% gel to apply to the eyelid margin once a day.
Results The adjusted mean change in eyelash length from baseline to 6 months was 0.77 mm in the bimatoprost group and −0.12 mm in the control group (P = 0.004). Adverse effects were experienced by 2 of 16 patients (12.5%) in the control group and 9 of 36 patients (25%) in the bimatoprost gel group. Mean change in IOP from baseline to 6 months was 0.685 mmHg in the control group and −2.04 mmHg in the bimatoprost group (P = 0.009).
Conclusions Bimatoprost gel was effective in enhancing eyelash growth. The most common adverse effect for the bimatoprost gel was conjunctival and eyelid hyperemia, while the most severe was recurrent anterior uveitis. Mean IOP was reduced in subjects using the bimatoprost gel.</description><identifier>ISSN: 1473-2130</identifier><identifier>EISSN: 1473-2165</identifier><identifier>DOI: 10.1111/j.1473-2165.2010.00487.x</identifier><identifier>PMID: 20618554</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Adult ; Aged ; Amides - administration & dosage ; Bimatoprost ; Cloprostenol - administration & dosage ; Cloprostenol - analogs & derivatives ; Double-Blind Method ; eyelash growth ; Eyelashes - drug effects ; Female ; Humans ; Male ; Middle Aged ; prostaglandins ; Treatment Outcome</subject><ispartof>Journal of cosmetic dermatology, 2010-06, Vol.9 (2), p.96-102</ispartof><rights>2010 Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4067-67c5a8def6fd32c7ea90f43a0956fe1c6c67399bb9e9e786661404083245bac30</citedby><cites>FETCH-LOGICAL-c4067-67c5a8def6fd32c7ea90f43a0956fe1c6c67399bb9e9e786661404083245bac30</cites></display><links><openurl>$$Topenurl_article</openurl><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>783</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20618554$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Woodward, Julie A</creatorcontrib><creatorcontrib>Haggerty, Chris J</creatorcontrib><creatorcontrib>Stinnett, Sandra S</creatorcontrib><creatorcontrib>Williams, Zinaria Y</creatorcontrib><title>Bimatoprost 0.03% gel for cosmetic eyelash growth and enhancement</title><title>Journal of cosmetic dermatology</title><addtitle>J Cosmet Dermatol</addtitle><description>Summary
Objective To evaluate a bimatoprost gel for enhancing eyelash growth, adverse effects, and change in intraocular pressure (IOP).
Methods Prospective, double‐masked, randomized controlled study. Fifty‐two patients without ocular disease were assigned a control or bimatoprost 0.03% gel to apply to the eyelid margin once a day.
Results The adjusted mean change in eyelash length from baseline to 6 months was 0.77 mm in the bimatoprost group and −0.12 mm in the control group (P = 0.004). Adverse effects were experienced by 2 of 16 patients (12.5%) in the control group and 9 of 36 patients (25%) in the bimatoprost gel group. Mean change in IOP from baseline to 6 months was 0.685 mmHg in the control group and −2.04 mmHg in the bimatoprost group (P = 0.009).
Conclusions Bimatoprost gel was effective in enhancing eyelash growth. The most common adverse effect for the bimatoprost gel was conjunctival and eyelid hyperemia, while the most severe was recurrent anterior uveitis. Mean IOP was reduced in subjects using the bimatoprost gel.</description><subject>Adult</subject><subject>Aged</subject><subject>Amides - administration & dosage</subject><subject>Bimatoprost</subject><subject>Cloprostenol - administration & dosage</subject><subject>Cloprostenol - analogs & derivatives</subject><subject>Double-Blind Method</subject><subject>eyelash growth</subject><subject>Eyelashes - drug effects</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>prostaglandins</subject><subject>Treatment Outcome</subject><issn>1473-2130</issn><issn>1473-2165</issn><fulltext>false</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><recordid>eNqNkM1OAjEUhRujEUVfwXRjXA220047XbhAFNQQYYFx2ZRyBwbnB6dDgLe3I8jabnrTnnPa8yGEKelQv-6XHcolC0Iqok5I_CkhPJad7Qm6OF6cHmdGWujSuSUhVCoanaNWSASNo4hfoO5jmpu6XFWlq7HPYbd4DhlOygrb0uVQpxbDDjLjFnhelZt6gU0xw1AsTGEhh6K-QmeJyRxcH_Y2-ug_T3ovwXA0eO11h4HlRMhASBuZeAaJSGYstBKMIglnhqhIJECtsEIypaZTBQpkLISgnHASs5BHU2MZaaO7fa7_6_caXK3z1FnIMlNAuXZaMqYE45x6ZbxXWt_KVZDoVeVbVjtNiW746aVu0OgGk2746V9-euutN4dH1tMcZkfjHzAveNgLNmkGu38H67dR78lP3h_s_amrYXv0m-pL-_4y0p_vA92PwzFTY6Yn5Ac7Loun</recordid><startdate>201006</startdate><enddate>201006</enddate><creator>Woodward, Julie A</creator><creator>Haggerty, Chris J</creator><creator>Stinnett, Sandra S</creator><creator>Williams, Zinaria Y</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201006</creationdate><title>Bimatoprost 0.03% gel for cosmetic eyelash growth and enhancement</title><author>Woodward, Julie A ; Haggerty, Chris J ; Stinnett, Sandra S ; Williams, Zinaria Y</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4067-67c5a8def6fd32c7ea90f43a0956fe1c6c67399bb9e9e786661404083245bac30</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Amides - administration & dosage</topic><topic>Bimatoprost</topic><topic>Cloprostenol - administration & dosage</topic><topic>Cloprostenol - analogs & derivatives</topic><topic>Double-Blind Method</topic><topic>eyelash growth</topic><topic>Eyelashes - drug effects</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>prostaglandins</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><creatorcontrib>Woodward, Julie A</creatorcontrib><creatorcontrib>Haggerty, Chris J</creatorcontrib><creatorcontrib>Stinnett, Sandra S</creatorcontrib><creatorcontrib>Williams, Zinaria Y</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of cosmetic dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>no_fulltext</fulltext></delivery><addata><au>Woodward, Julie A</au><au>Haggerty, Chris J</au><au>Stinnett, Sandra S</au><au>Williams, Zinaria Y</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Bimatoprost 0.03% gel for cosmetic eyelash growth and enhancement</atitle><jtitle>Journal of cosmetic dermatology</jtitle><addtitle>J Cosmet Dermatol</addtitle><date>2010-06</date><risdate>2010</risdate><volume>9</volume><issue>2</issue><spage>96</spage><epage>102</epage><pages>96-102</pages><issn>1473-2130</issn><eissn>1473-2165</eissn><abstract>Summary
Objective To evaluate a bimatoprost gel for enhancing eyelash growth, adverse effects, and change in intraocular pressure (IOP).
Methods Prospective, double‐masked, randomized controlled study. Fifty‐two patients without ocular disease were assigned a control or bimatoprost 0.03% gel to apply to the eyelid margin once a day.
Results The adjusted mean change in eyelash length from baseline to 6 months was 0.77 mm in the bimatoprost group and −0.12 mm in the control group (P = 0.004). Adverse effects were experienced by 2 of 16 patients (12.5%) in the control group and 9 of 36 patients (25%) in the bimatoprost gel group. Mean change in IOP from baseline to 6 months was 0.685 mmHg in the control group and −2.04 mmHg in the bimatoprost group (P = 0.009).
Conclusions Bimatoprost gel was effective in enhancing eyelash growth. The most common adverse effect for the bimatoprost gel was conjunctival and eyelid hyperemia, while the most severe was recurrent anterior uveitis. Mean IOP was reduced in subjects using the bimatoprost gel.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>20618554</pmid><doi>10.1111/j.1473-2165.2010.00487.x</doi><tpages>7</tpages></addata></record> |
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| ispartof | Journal of cosmetic dermatology, 2010-06, Vol.9 (2), p.96-102 |
| issn | 1473-2130 1473-2165 |
| language | eng |
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| subjects | Adult Aged Amides - administration & dosage Bimatoprost Cloprostenol - administration & dosage Cloprostenol - analogs & derivatives Double-Blind Method eyelash growth Eyelashes - drug effects Female Humans Male Middle Aged prostaglandins Treatment Outcome |
| title | Bimatoprost 0.03% gel for cosmetic eyelash growth and enhancement |
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