Bimatoprost 0.03% gel for cosmetic eyelash growth and enhancement

Summary Objective  To evaluate a bimatoprost gel for enhancing eyelash growth, adverse effects, and change in intraocular pressure (IOP). Methods  Prospective, double‐masked, randomized controlled study. Fifty‐two patients without ocular disease were assigned a control or bimatoprost 0.03% gel to ap...

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Bibliographic Details
Published in:Journal of cosmetic dermatology 2010-06, Vol.9 (2), p.96-102
Main Authors: Woodward, Julie A, Haggerty, Chris J, Stinnett, Sandra S, Williams, Zinaria Y
Format: Article
Language:English
Subjects:
Adult
Aged
Amides - administration & dosage
Bimatoprost
Cloprostenol - administration & dosage
Cloprostenol - analogs & derivatives
Double-Blind Method
eyelash growth
Eyelashes - drug effects
Female
Humans
Male
Middle Aged
prostaglandins
Treatment Outcome
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Summary:Summary Objective  To evaluate a bimatoprost gel for enhancing eyelash growth, adverse effects, and change in intraocular pressure (IOP). Methods  Prospective, double‐masked, randomized controlled study. Fifty‐two patients without ocular disease were assigned a control or bimatoprost 0.03% gel to apply to the eyelid margin once a day. Results  The adjusted mean change in eyelash length from baseline to 6 months was 0.77 mm in the bimatoprost group and −0.12 mm in the control group (P = 0.004). Adverse effects were experienced by 2 of 16 patients (12.5%) in the control group and 9 of 36 patients (25%) in the bimatoprost gel group. Mean change in IOP from baseline to 6 months was 0.685 mmHg in the control group and −2.04 mmHg in the bimatoprost group (P = 0.009). Conclusions  Bimatoprost gel was effective in enhancing eyelash growth. The most common adverse effect for the bimatoprost gel was conjunctival and eyelid hyperemia, while the most severe was recurrent anterior uveitis. Mean IOP was reduced in subjects using the bimatoprost gel.
ISSN:1473-2130
1473-2165
DOI:10.1111/j.1473-2165.2010.00487.x