In vivo biofilm composition of Aspergillus fumigatus

The in vivo composition of the mycelial extracellular matrix (ECM) of Aspergillus fumigatus during host invasion is reported here for the first time. A new galactosaminogalactan and the galactomannan were the major polysaccharides of the in vivo ECM. The composition of the ECM in vivo varied with th...

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Bibliographic Details
Published in:Cellular microbiology 2010-03, Vol.12 (3), p.405-410
Main Authors: Loussert, Céline, Schmitt, Christine, Prevost, Marie-Christine, Balloy, Viviane, Fadel, Elie, Philippe, Bruno, Kauffmann-Lacroix, Catherine, Latgé, Jean Paul, Beauvais, Anne
Format: Article
Language:English
Subjects:
Animals
Aspergillosis
Aspergillus fumigatus
Aspergillus fumigatus - growth & development
Aspergillus fumigatus - metabolism
Aspergillus fumigatus - physiology
Biofilms
Biofilms - growth & development
Extracellular matrix
Extracellular Matrix - chemistry
Humans
Mannans - analysis
Mice
Mycelia
Polysaccharides
Polysaccharides - analysis
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Summary:The in vivo composition of the mycelial extracellular matrix (ECM) of Aspergillus fumigatus during host invasion is reported here for the first time. A new galactosaminogalactan and the galactomannan were the major polysaccharides of the in vivo ECM. The composition of the ECM in vivo varied with the aspergillosis pathologies.
ISSN:1462-5814
1462-5822
DOI:10.1111/j.1462-5822.2009.01409.x