In vivo Dentin Remineralization by Calcium-phosphate Cement

Minimally invasive caries-removal procedures remove only caries-infected dentin and preserve caries-affected dentin that becomes remineralized. Dental cements containing calcium phosphate promote remineralization. This study evaluated the in vivo remineralization capacity of resin-based calcium-phos...

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Bibliographic Details
Published in:Journal of dental research 2010-03, Vol.89 (3), p.286-291
Main Authors: Peters, M.C., Bresciani, E., Barata, T.J.E., Fagundes, T.C., Navarro, R.L., Navarro, M.F.L., Dickens, S.H.
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Calcium - analysis
Calcium phosphates
Calcium Phosphates - analysis
Calcium Phosphates - therapeutic use
Cement
Composite materials
Dental caries
Dental Caries - therapy
Dental Cavity Lining
Dental Cavity Preparation - methods
Dental cement
Dental pulp
Dental Restoration, Permanent - methods
Dental restorative materials
Dentin
Dentin - chemistry
Dentin - drug effects
Dentistry
Electron probe
Electron Probe Microanalysis
Facial bones, jaws, teeth, parodontium: diseases, semeiology
Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics
Humans
Linear Models
Maxillofacial surgery. Dental surgery. Orthodontics
Medical sciences
Non tumoral diseases
Otorhinolaryngology. Stomatology
Phosphorus
Phosphorus - analysis
Phosphorus content
Prospective Studies
Remineralization
Resin Cements - chemistry
Resin Cements - therapeutic use
Statistics, Nonparametric
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Teeth
Tooth Remineralization - methods
Treatment Outcome
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Summary:Minimally invasive caries-removal procedures remove only caries-infected dentin and preserve caries-affected dentin that becomes remineralized. Dental cements containing calcium phosphate promote remineralization. This study evaluated the in vivo remineralization capacity of resin-based calcium-phosphate cement (Ca-P) used for indirect pulp-capping. Carious and sound teeth indicated for extraction were randomly restored with the Ca-P base or without base (control), followed by adhesive restoration. Study teeth were extracted after three months, followed by elemental analysis of the cavity floor. Mineral content of affected or sound dentin at the cavity floor was quantified by electron probe micro-analysis to 100-μm depth. After three months, caries-affected dentin underneath the Ca-P base showed significantly increased calcium and phosphorus content to a depth of 30 μm. Mineral content of treated caries-affected dentin was in the range of healthy dentin, revealing the capacity of Ca-P base to promote remineralization of caries-affected dentin.
ISSN:0022-0345
1544-0591
DOI:10.1177/0022034509360155