Paratesticular desmoplastic small round cell tumour: case report with literature review

Desmoplastic small round cell tumors are rare aggressive cancers of adolescence and early adulthood. It has recently been separated from other small round cell tumors because of its pathological characteristics and clinical features. They are usually intra-abdominal tumors affecting young people and...

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Bibliographic Details
Published in:Cancer radiothérapie 2010-04, Vol.14 (2), p.111-114
Main Authors: Rais, H, Elmansouri, F, Belaabidia, B, Essadki, O, Oussehal, A, Sarf, I
Format: Article
Language:fre
Subjects:
Adolescent
Adult
Cell Division
Child
Epididymis - diagnostic imaging
Epididymis - pathology
Humans
Immunohistochemistry
Keratins - genetics
Male
Orchiectomy
Reverse Transcriptase Polymerase Chain Reaction
Testicular Neoplasms - diagnostic imaging
Testicular Neoplasms - pathology
Testicular Neoplasms - radiotherapy
Testicular Neoplasms - surgery
Tomography, X-Ray Computed
Treatment Outcome
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Summary:Desmoplastic small round cell tumors are rare aggressive cancers of adolescence and early adulthood. It has recently been separated from other small round cell tumors because of its pathological characteristics and clinical features. They are usually intra-abdominal tumors affecting young people and have classically been associated with a bad prognosis. However, in recent years there have been reports on desmoplastic small round cell tumors affecting other body regions, including the paratesticular area. We report the case of a 27-year-old male who consulted on a progressive enlargement of the right hemiscrotum. He referred no previous urological symptoms and had no systemic symptomatology. Physical examination revealed a round elastic firm 1-cm mass of the epididymis, which was excised. A computed tomography scan showed a para-aortic mass of 1cm. Histological and immunohistochemical diagnosis confirmed a desmoplastic small round cell tumor. The patient received chemotherapy. Today, 6 months after diagnosis the patient remains well and free of disease. Recent reviews on desmoplastic small round cell tumors affecting the paratesticular area have shown a better prognosis for tumors of this origin compared to abdominal ones. We should include this lesion among the differential diagnosis of paratesticular tumors, mainly in children and adolescents.
ISSN:1769-6658
DOI:10.1016/j.canrad.2009.09.008