Low serum magnesium level predicts major adverse cardiac events after coronary artery bypass graft surgery

Despite improved myocardial protection strategies and enhanced surgical techniques, mortality after coronary artery bypass graft surgery (CABG) remains essentially unchanged. This may be because of the increasing age of patients who undergo primary CABG. Magnesium is an important regulator of vascul...

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Bibliographic Details
Published in:The American heart journal 2003-06, Vol.145 (6), p.1108-1113
Main Authors: Booth, John V, Phillips-Bute, Barbara, McCants, Charles B, Podgoreanu, Mihai V, Smith, Peter K, Mathew, Joseph P, Newman, Mark F
Format: Article
Language:English
Subjects:
Aged
Biological and medical sciences
Biomarkers - blood
Cause of Death
Chronic obstructive pulmonary disease
Coronary Artery Bypass - mortality
Coronary vessels
Female
Heart attacks
Humans
Magnesium - blood
Male
Medical sciences
Middle Aged
Mortality
Myocardial Infarction - blood
Myocardial Infarction - mortality
Predictive Value of Tests
Proportional Hazards Models
Prospective Studies
Statistics, Nonparametric
Studies
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the heart
Time Factors
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Summary:Despite improved myocardial protection strategies and enhanced surgical techniques, mortality after coronary artery bypass graft surgery (CABG) remains essentially unchanged. This may be because of the increasing age of patients who undergo primary CABG. Magnesium is an important regulator of vascular tone, reperfusion injury, and thrombosis. Therefore, we decided to investigate the relationship between serum magnesium levels and major adverse cardiac events (MACE) after CABG. A total of 957 patients undergoing primary CABG were prospectively recruited into the Duke Cardiovascular database and had daily serum magnesium levels measured. Low magnesium was defined as
ISSN:0002-8703
1097-6744
DOI:10.1016/S0002-8703(03)00077-2