ABCD2 Score Predicts Severity Rather Than Risk of Early Recurrent Events After Transient Ischemic Attack

The ABCD(2) score predicts the early risk of stroke after transient ischemic attack (TIA). However, data on the severity of recurrent events would also be useful. Do patients with high scores also have more severe early recurrent strokes, perhaps further justifying hospital admission? Do patients wi...

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Bibliographic Details
Published in:Stroke (1970) 2010-05, Vol.41 (5), p.851-856
Main Authors: CHANDRATHEVA, Arvind, GERAGHTY, Olivia C, LUENGO-FERNANDEZ, Ramon, ROTHWELL, Peter M
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biological and medical sciences
Blood. Blood coagulation. Reticuloendothelial system
Cohort Studies
Female
Follow-Up Studies
Humans
Ischemic Attack, Transient - diagnosis
Ischemic Attack, Transient - prevention & control
Male
Medical sciences
Middle Aged
Neurology
Pharmacology. Drug treatments
Predictive Value of Tests
Prospective Studies
Risk Factors
Secondary Prevention
Severity of Illness Index
Stroke - diagnosis
Stroke - prevention & control
Time Factors
Vascular diseases and vascular malformations of the nervous system
Young Adult
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Summary:The ABCD(2) score predicts the early risk of stroke after transient ischemic attack (TIA). However, data on the severity of recurrent events would also be useful. Do patients with high scores also have more severe early recurrent strokes, perhaps further justifying hospital admission? Do patients with low scores have a low early risk of recurrent TIA as well as recurrent stroke? We completed a prospective, population-based study in Oxfordshire, England, of 500 consecutive patients presenting with TIA from April 1, 2002, by using multiple methods of case ascertainment (Oxford Vascular Study). Recurrent TIA, minor stroke, and major stroke (National Institutes of Health Stroke Scale score >3 at the time of first assessment) were identified by face-to-face follow-up. Predictive value was expressed as the area under the receiver operating characteristic curve. Of 500 patients with TIA, 55 had a recurrent TIA (11.0%; 95% CI, 8.3% to 13.7%) and 50 had a recurrent stroke (10.0%; 95% CI, 7.5% to 12.0%) within 7 days. The ABCD(2) score was highly predictive of major recurrent stroke (area under the receiver operating characteristic curve=0.80; 95% CI, 0.72 to 0.87, P
ISSN:0039-2499
1524-4628
DOI:10.1161/STROKEAHA.109.570010