Perivascular epithelioid cell tumor of abdominal origin

Abstract Perivascular epithelioid tumor is not a common disease; therefore, large series are not available in the literature, and most are case reports. Histologic characteristics of these neoplasms are positivity to melanogenic (HMB-45) and muscle stains. All these neoplasms have the characteristic...

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Bibliographic Details
Published in:Annals of diagnostic pathology 2010-06, Vol.14 (3), p.173-177
Main Authors: de León, David Cantú, MD, Pérez-Montiel, Delia, MD, Bandera, Arfy, MD, Villegas, Carlos, MD, Gonzalez-Conde, Esther, MD, Vilchis, José Chanona, MD
Format: Article
Language:English
Subjects:
Adult
Aged
Biomarkers, Tumor - metabolism
Combined Modality Therapy
Epithelioid Cells - metabolism
Epithelioid Cells - pathology
Fatal Outcome
Female
Humans
Immunohistochemistry
Malignant
Pathology
PEComa
Pelvic Neoplasms - metabolism
Pelvic Neoplasms - pathology
Pelvic Neoplasms - therapy
Pelvis
Perivascular Epithelioid Cell Neoplasms - metabolism
Perivascular Epithelioid Cell Neoplasms - secondary
Perivascular Epithelioid Cell Neoplasms - therapy
Tomography, X-Ray Computed
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Summary:Abstract Perivascular epithelioid tumor is not a common disease; therefore, large series are not available in the literature, and most are case reports. Histologic characteristics of these neoplasms are positivity to melanogenic (HMB-45) and muscle stains. All these neoplasms have the characteristic perivascular epithelioid cell or “PEC,” but the term myomelanocyte tumor has been proposed because of the immunohistochemistry expression. Females are affected more commonly than males. The uterus seems to be one of the most common organs affected. Its clinical behavior is uncertain, and standard treatment has not been established as well as criteria for malignancy. We report 3 cases of abdominal PEComa, 1 of them with benign clinical outcome and 2 with an aggressive behavior.
ISSN:1092-9134
1532-8198
DOI:10.1016/j.anndiagpath.2010.02.007