Comparison of Exercise Electrocardiography, Technetium-99m Sestamibi Single Photon Emission Computed Tomography, and Dobutamine and Dipyridamole Echocardiography for Detection of Coronary Artery Disease in Hypertensive Women

To assess the performance of currently used stress tests for the detection of coronary artery disease (CAD) in a series of female hypertensive patients. We performed exercise electrocardiography (ECG), technetium-99m sestamibi (MIBI) single photon emission computed tomography, dobutamine and dipyrid...

Full description

Saved in:
Bibliographic Details
Published in:The American journal of cardiology 2010-05, Vol.105 (9), p.1254-1260
Main Authors: Lu, Chunzeng, MD, PhD, Lu, Fei, MD, Fragasso, Gabriele, MD, Dabrowski, Pawel, MD, Di Bello, Vitantonio, MD, Chierchia, Sergio L., MD, Gianolli, Luigi, MD, Marzilli, Mario, MD, Balbarini, Alberto, MD
Format: Article
Language:English
Subjects:
Arterial hypertension. Arterial hypotension
Atoms & subatomic particles
Biological and medical sciences
Blood and lymphatic vessels
Cardiology
Cardiology. Vascular system
Cardiotonic Agents
Cardiovascular
Cardiovascular disease
Cardiovascular system
Coronary Artery Disease - diagnosis
Coronary Artery Disease - etiology
Coronary heart disease
Diagnosis, Differential
Dipyridamole
Dobutamine
Echocardiography, Stress - methods
Electrocardiography - methods
Exercise Test - methods
Female
Heart
Humans
Hypertension
Hypertension - complications
Investigative techniques, diagnostic techniques (general aspects)
Medical sciences
Middle Aged
Prospective Studies
Radiopharmaceuticals
Reproducibility of Results
Technetium Tc 99m Sestamibi
Tomography
Tomography, Emission-Computed, Single-Photon - methods
Ultrasonic investigative techniques
Vasodilator Agents
Women
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To assess the performance of currently used stress tests for the detection of coronary artery disease (CAD) in a series of female hypertensive patients. We performed exercise electrocardiography (ECG), technetium-99m sestamibi (MIBI) single photon emission computed tomography, dobutamine and dipyridamole echocardiography, and coronary angiography in 76 hypertensive women. Of the 76 study patients, 31 (41%) had significant CAD. The sensitivity of exercise ECG (81%), MIBI scanning (90%), and dobutamine echocardiography (87%) was greater than that of dipyridamole echocardiography (61%). This finding resulted from the lower sensitivity of dipyridamole echocardiography in the detection of single-vessel CAD (47% vs 76%, 88%, and 82% for the other 3 methods). In contrast, the sensitivity of the 4 tests was similar in the detection of multivessel CAD. The specificity of exercise ECG (56%) and MIBI scanning (53%) was less than that of dobutamine (82%, both p
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2009.12.033