Hypertension and aldosterone levels in women with early-onset androgenetic alopecia

Summary Background Few studies have analysed the relationship between androgenetic alopecia (AGA) in women and cardiovascular disease. There is reported to be an elevated prevalence of hypertension among men with AGA, and it has been proposed that both phenomena may be explained by the presence of...

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Published in:	British journal of dermatology (1951) 2010-04, Vol.162 (4), p.786-789
Main Authors:	Arias-Santiago, S., Gutiérrez-Salmerón, M.T., Buendía-Eisman, A., Girón-Prieto, M.S., Naranjo-Sintes, R.
Format:	Article
Language:	eng
Subjects:	Adult Age Factors Aldosterone - blood aldosterone levels Alopecia - complications Arterial hypertension. Arterial hypotension Biological and medical sciences Biomarkers - blood Blood and lymphatic vessels Blood Pressure - physiology Cardiology. Vascular system cardiovascular risk factors Case-Control Studies Dermatology Female Hair and nails disorders Humans hypertension Hypertension - etiology Hypertension - metabolism Male Medical sciences Middle Aged Sex Factors spironolactone Time Factors women androgenetic alopecia
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Summary:	Summary Background Few studies have analysed the relationship between androgenetic alopecia (AGA) in women and cardiovascular disease. There is reported to be an elevated prevalence of hypertension among men with AGA, and it has been proposed that both phenomena may be explained by the presence of hyperaldosteronism. However, no data on blood pressure (BP) and aldosterone levels in women with AGA have been published to date. Objectives The objective of this study was to evaluate aldosterone levels and the presence of systolic and diastolic hypertension in women with early‐onset AGA and in healthy controls. Patients and methods This case–control study included 40 women with AGA and 40 healthy controls from the Department of Dermatology of San Cecilio Hospital, Granada, Spain. Results Patients with AGA showed significantly higher systolic BP values (139·43 vs. 107·80 mmHg; P
ISSN:	0007-0963 1365-2133