Narrowband ultraviolet B course improves vitamin D balance in women in winter

Summary Background  Vitamin D insufficiency is common in winter in the Nordic countries. Objectives  To examine whether a short course of narrowband ultraviolet B (NB‐UVB) improves vitamin D balance. Methods  Fifty‐six healthy, white women (mean age 41 years) volunteered and 53 completed the study....

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Bibliographic Details
Published in:British journal of dermatology (1951) 2010-04, Vol.162 (4), p.848-853
Main Authors: Vähävihu, K., Ylianttila, L., Kautiainen, H., Viljakainen, H., Lamberg-Allardt, C., Hasan, T., Tuohimaa, P., Reunala, T., Snellman, E.
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
calcidiol
Calcifediol - blood
Dermatology
Dose-Response Relationship, Radiation
Female
Finland
Humans
Medical sciences
Middle Aged
Seasons
skin
Skin - radiation effects
Sunbathing
Treatment Outcome
ultraviolet B radiation
Ultraviolet Rays
Ultraviolet Therapy - methods
vitamin D
Vitamin D - biosynthesis
Vitamin D - blood
Vitamin D Deficiency - blood
Vitamin D Deficiency - therapy
Young Adult
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Summary:Summary Background  Vitamin D insufficiency is common in winter in the Nordic countries. Objectives  To examine whether a short course of narrowband ultraviolet B (NB‐UVB) improves vitamin D balance. Methods  Fifty‐six healthy, white women (mean age 41 years) volunteered and 53 completed the study. NB‐UVB exposures were given on seven consecutive days either on the whole body (n = 19), on the head and arms (n = 9) or on the abdomen (n = 14). Similarly, seven solar simulator exposures were given on the face and arms (n = 11). The cumulative UVB dose was 13 standard erythema doses in all regimens. Serum calcidiol (25‐hydroxyvitamin D) concentration was measured by radioimmunoassay before and after the NB‐UVB exposures. Follow‐up samples were taken from the whole‐body NB‐UVB group at 2 months. Results  At onset 41 women (77%) had vitamin D insufficiency (calcidiol
ISSN:0007-0963
1365-2133
DOI:10.1111/j.1365-2133.2010.09629.x