Obsessive-Compulsive Disorder in Adolescent Schizophrenia Patients

OBJECTIVE: The co-occurrence of obsessive-compulsive disorder (OCD) in adult patients with schizophrenia has been increasingly recognized. However, the rate of OCD comorbidity in adolescent schizophrenia patients has yet to be systematically evaluated. METHOD: The rate of DSM-IV OCD was evaluated in...

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Bibliographic Details
Published in:The American journal of psychiatry 2003-05, Vol.160 (5), p.1002-1004
Main Authors: Nechmad, Allon, Ratzoni, Gideon, Poyurovsky, Michael, Meged, Sorin, Avidan, Gideon, Fuchs, Camil, Bloch, Yuval, Weizman, Ronit
Format: Article
Language:English
Subjects:
Adolescent
Adolescents
Adult and adolescent clinical studies
Age Factors
Age of Onset
Anxiety disorders. Neuroses
Biological and medical sciences
Comorbidity
Diagnostic and Statistical Manual of Mental Disorders
Female
Hospitalization
Humans
Male
Medical sciences
Neuroses
Obsessive compulsive disorder
Obsessive-Compulsive Disorder - diagnosis
Obsessive-Compulsive Disorder - epidemiology
Obsessive-compulsive disorders
Obsessive-Compulsive neuroses
Psychiatric Status Rating Scales
Psychiatry
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Psychoses
Psychotic Disorders - diagnosis
Psychotic Disorders - epidemiology
Schizoaffective disorder
Schizophrenia
Schizophrenia - diagnosis
Schizophrenia - epidemiology
Severity of Illness Index
Teenagers
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Summary:OBJECTIVE: The co-occurrence of obsessive-compulsive disorder (OCD) in adult patients with schizophrenia has been increasingly recognized. However, the rate of OCD comorbidity in adolescent schizophrenia patients has yet to be systematically evaluated. METHOD: The rate of DSM-IV OCD was evaluated in 50 adolescent inpatients with schizophrenia or schizoaffective disorder. The severity of schizophrenia and OCD symptoms was assessed with the Scale for the Assessment of Positive Symptoms, Scale for the Assessment of Negative Symptoms (SANS), and Yale-Brown Obsessive Compulsive Scale. RESULTS: Thirteen schizophrenia patients (26.0%) also met the DSM-IV criteria for OCD. This subgroup scored significantly higher on the SANS subscale for affective flattening or blunting. The total SANS score positively correlated with the total Yale-Brown Obsessive Compulsive Scale score. CONCLUSIONS: A substantial proportion of adolescent schizophrenia inpatients have concomitant OCD. A prospective study is needed to evaluate the clinical course, response to treatment, and prognosis for this complex disorder.
ISSN:0002-953X
1535-7228
DOI:10.1176/appi.ajp.160.5.1002