Comparison of temporal filtering methods for dynamic contrast MRI myocardial perfusion studies

Dynamic contrast myocardial perfusion studies may benefit from methods that speed up the acquisition. Unaliasing by Fourier encoding the overlaps using the temporal dimension (UNFOLD), and a similar linear interpolation method have been shown to be effective at reducing the number of phase encodes n...

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Bibliographic Details
Published in:Magnetic resonance in medicine 2003-05, Vol.49 (5), p.895-902
Main Authors: Di Bella, E.V.R., Wu, Y.J., Alexander, A.L., Parker, D.L., Green, D., McGann, C.J.
Format: Article
Language:English
Subjects:
Algorithms
Animals
Biological and medical sciences
Dogs
Filtration - instrumentation
gadolinium
gadolinium, rapid imaging
Heart - physiology
Heart - physiopathology
Humans
Image Enhancement
Image Interpretation, Computer-Assisted - instrumentation
Image Interpretation, Computer-Assisted - methods
Magnetic Resonance Imaging - instrumentation
Magnetic Resonance Imaging - methods
Medical sciences
Movement - physiology
myocardial perfusion imaging
Myocardium
rapid imaging
Respiration
temporal filtering
UNFOLD
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Summary:Dynamic contrast myocardial perfusion studies may benefit from methods that speed up the acquisition. Unaliasing by Fourier encoding the overlaps using the temporal dimension (UNFOLD), and a similar linear interpolation method have been shown to be effective at reducing the number of phase encodes needed for cardiac wall motion studies by using interleaved sampling and temporal filtering. Here such methods are evaluated in cardiac dynamic contrast studies, with particular regard to the effects of the choice of filter and the interframe motion. Four different filters were evaluated using a motion‐free canine study. Full k‐space was acquired and then downsampled to allow for a measure of truth. The different filters gave nearly equivalent images and quantitative flow estimates compared to full k‐space. The effect of respiratory motion on these schemes was graphically depicted, and the performance of the four temporal filters was evaluated in seven human subjects with respiratory motion present. The four filters provided images of similar quality. However, none of the filters were effective at eliminating motion artifacts. Motion registration methods or motion‐free acquisitions may be necessary to make these reduced FOV approaches clinically useful. Magn Reson Med 49:895–902, 2003. © 2003 Wiley‐Liss, Inc.
ISSN:0740-3194
1522-2594
DOI:10.1002/mrm.10439