Synthesis of some carbamates of myo-inositol

The syntheses are described of the 1- O-carbamoyl ( 11), 1- O-carbamoyl-2- O-stearoyl ( 10), 1- O-)acetylcarbamoyl)-2- O-stearoyl ( 12), 1- O-(heptylcarbamoy) ( 13), 2- O-(heptylcarbamoyl) ( 14), 1,2-di O-(heptylcrbamoyl) ( 15), and 1- O-(octadecylcarbamoyl) ( 16) derivatives of myo-inositol. None o...

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Bibliographic Details
Published in:Carbohydrate research 1992-04, Vol.228 (2), p.371-376
Main Authors: Brufani, Mario, Cesta, Maria C., Donnarumma, Lucia, Filocamo, Luigi, Gostoli, Gianluca, Lappa, Sperandina, Ferrari, Enrico, Pagella, Pier G.
Format: Article
Language:English
Subjects:
Carbamates - chemical synthesis
Carbamates - pharmacology
Carbohydrates with 4, 5, 6, ... C atoms, dissacharides and oligosaccharides
Carbohydrates. Nucleosides and nucleotides
Chemistry
Exact sciences and technology
Inositol - analogs & derivatives
Inositol - chemical synthesis
Inositol - pharmacology
Molecular Structure
Organic chemistry
Preparations and properties
Type C Phospholipases - antagonists & inhibitors
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Summary:The syntheses are described of the 1- O-carbamoyl ( 11), 1- O-carbamoyl-2- O-stearoyl ( 10), 1- O-)acetylcarbamoyl)-2- O-stearoyl ( 12), 1- O-(heptylcarbamoy) ( 13), 2- O-(heptylcarbamoyl) ( 14), 1,2-di O-(heptylcrbamoyl) ( 15), and 1- O-(octadecylcarbamoyl) ( 16) derivatives of myo-inositol. None of these compounds has significant activity against phospholipase C.
ISSN:0008-6215
1873-426X
DOI:10.1016/0008-6215(92)84131-B