Continuous thermodilution cardiac output measurement in sheep

A technique has been developed to continuously measure cardiac output by means of the principles of thermodilution. Pulmonary artery catheters were modified by placing a 10 cm filament near the usual injectate port. Small amounts of heat were infused according to a randomly repeating binary on-off s...

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Bibliographic Details
Published in:The Journal of thoracic and cardiovascular surgery 1992-08, Vol.104 (2), p.315-320
Main Authors: Yelderman, Mark, Quinn, Michael D., McKown, Russell C., Eberhart, Robert C., Dollar, Michael L.
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Cardiac & Cardiovascular Systems
Cardiac Output
Cardiovascular system
Cardiovascular System & Cardiology
Catheterization, Swan-Ganz
Heart Rate
Investigative techniques of hemodynamics
Investigative techniques, diagnostic techniques (general aspects)
Life Sciences & Biomedicine
Medical sciences
Monitoring, Physiologic - methods
Pulmonary Artery
Regression Analysis
Respiratory System
Science & Technology
Sheep
Signal Processing, Computer-Assisted
Surgery
Thermodilution - methods
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Summary:A technique has been developed to continuously measure cardiac output by means of the principles of thermodilution. Pulmonary artery catheters were modified by placing a 10 cm filament near the usual injectate port. Small amounts of heat were infused according to a randomly repeating binary on-off sequence. The distal blood temperature was recorded and cross-correlated with the heat waveform to produce a dilution curve and calculate cardiac output. The technique was compared with bolus thermodilution in seven sheep. Cardiac output ranged from 1.5 to 13.2 L/min, and heart rate varied from 59 to 180 beats/min. The linear regression between the data obtained by the two methods is represented by the equation y = 1.00x + 0.13; the correlation coefficient, R, is 0.97, and the p value is
ISSN:0022-5223
1097-685X
DOI:10.1016/S0022-5223(19)34783-X