Influence of portal pressure change on intestinal permeability in patients with portal hypertension

To investigate intestinal permeability in patients with portal hypertension and its relationship with portal pressure. Twenty patients with portal hypertension were divided into two groups (A, B), 10 patients per group. In group A, patients were treated with combined transjugular intrahepatic portos...

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Bibliographic Details
Published in:Hepatobiliary & pancreatic diseases international 2002-11, Vol.1 (4), p.510-514
Main Authors: Xu, Wei-Hua, Wu, Xing-Jiang, Li, Jie-Shou
Format: Article
Language:English
Subjects:
Adult
Blood Pressure
Female
Humans
Hypertension, Portal - physiopathology
Hypertension, Portal - surgery
Intestines - metabolism
Male
Middle Aged
Permeability
Portal Vein - physiopathology
Portasystemic Shunt, Transjugular Intrahepatic
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Summary:To investigate intestinal permeability in patients with portal hypertension and its relationship with portal pressure. Twenty patients with portal hypertension were divided into two groups (A, B), 10 patients per group. In group A, patients were treated with combined transjugular intrahepatic portosystemic shunt (TIPS) and modified Sugiura. In group B, patients were treated with modified Sugiura only. Intestinal permeability was assessed before operation, two weeks after TIPS, and two weeks after modified Sugiura; 20 healthy control subjects were also assessed. Intestinal permeability was significantly higher in the patients than in the control group (P
ISSN:1499-3872