Cat scratch disease: analysis of 130 seropositive cases

To clarify the clinical manifestations of cat scratch disease (CSD), we evaluated a total of 130 seropositive patients with CSD. The patients' ages ranged from 1 to 68 years; 103 (79.2%) were under 18 years of age. CSD occurred predominantly in the fall and winter months. Regional lymphadenopat...

Full description

Saved in:
Bibliographic Details
Published in:Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2002-12, Vol.8 (4), p.349-352
Main Authors: Murakami, Kyoko, Furuya, Tomoko, Kawauchi, Shigeto, Sasaki, Kohsuke, Tsukahara, Masato, Iino, Hidechika, Ishida, Chizuru, Tsujino, Kumiko, Umeda, Akiko, Tsuneoka, Hidehiro
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Animals
Antibodies, Bacterial - blood
Bacterial diseases
Bartonella henselae infection
Bartonellosis
Biological and medical sciences
Cat scratch disease
Cat-Scratch Disease - complications
Cat-Scratch Disease - diagnosis
Cat-Scratch Disease - immunology
Cats
Child
Child, Preschool
Female
Fluorescent Antibody Technique, Indirect
Human bacterial diseases
Humans
Indirect fluorescent antibody (IFA)
Infant
Infectious diseases
Male
Medical sciences
Middle Aged
Tropical bacterial diseases
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To clarify the clinical manifestations of cat scratch disease (CSD), we evaluated a total of 130 seropositive patients with CSD. The patients' ages ranged from 1 to 68 years; 103 (79.2%) were under 18 years of age. CSD occurred predominantly in the fall and winter months. Regional lymphadenopathy was noted in 110 (84.6%) of the cases, and the most common sites were the neck (33%), axillary (27%), and inguinal (18%) regions. One hundred of the patients (77%) had general symptoms, such as fever, headache, and malaise. The clinical manifestations of CSD showed a wide spectrum from typical or classical CSD, with regional lymphadenopathy, to atypical or systemic CSD. Of the 130 cases, 103 (79.2%) were typical CSD and 27 (20.8%) were atypical CSD. Atypical cases of CSD were commonly reported as fever of unknown origin (37.0%), neuroretinitis (22.2%), encehalopathy (14.8%), hepatosplenic granuloma (11.1%), and Parinaud's oculoglandular syndrome (7.4%). Fever of unknown origin or prolonged fever lasting more than 14 days was evident in 27 (20.8%) of the 130 cases in this study. Eleven of the 27 cases lacked lymphadenopathy. Our findings suggest that CSD is not a rare disease in Japan. The indirect fluorescent antibody (IFA) test to detect Bartonella species may provide a prompt diagnosis of CSD and facilitate appropriate therapy.
ISSN:1341-321X
1437-7780
DOI:10.1007/s10156-002-0194-6