Do vestibular otolith organs participate in human orthostatic blood pressure control?

We hypothesized that vestibular otolith organ stimulation contributes to human orthostatic responses. Twelve subjects underwent three 60° upright tilts: (1) with the neck flexed from 0° to 30° relative to the body during 60° tilt, such that the head moved from horizontal to 90° above horizontal (0 t...

Full description

Saved in:
Bibliographic Details
Published in:Autonomic neuroscience 2002-09, Vol.100 (1), p.77-83
Main Authors: Watenpaugh, Donald E, Cothron, Adriena V, Wasmund, Stephen L, Wasmund, Wendy L, Carter, Robert, Muenter, Nicolette K, Smith, Michael L
Format: Article
Language:English
Subjects:
Adult
Analysis of Variance
Biological and medical sciences
Blood Pressure - physiology
Cardiovascular Physiological Phenomena
Dizziness - physiopathology
Female
Fundamental and applied biological sciences. Psychology
Gravity
Head-up tilt
Heart rate
Hemodynamics
Humans
Life Sciences (General)
Male
Motor control and motor pathways. Reflexes. Control centers of vegetative functions. Vestibular system and equilibration
Muscle sympathetic nerve activity
Muscle, Skeletal - physiology
Otolithic Membrane - physiology
Posture - physiology
Space life sciences
Supine Position - physiology
Sympathetic Nervous System - physiology
Vertebrates: nervous system and sense organs
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We hypothesized that vestibular otolith organ stimulation contributes to human orthostatic responses. Twelve subjects underwent three 60° upright tilts: (1) with the neck flexed from 0° to 30° relative to the body during 60° tilt, such that the head moved from horizontal to 90° above horizontal (0 to 1 Gz otolith stimulation); (2) with the head and body aligned, such that they tilted together to 60° (0 to 0.87 Gz otolith stimulation); and (3) with the neck flexed 30° relative to the body during supine conditions, and the neck then extended to −30° during 60° body tilting, such that the head remained at 30° above horizontal throughout body tilting (constant 0.5 Gz otolith stimulation). All three tilt procedures increased thoracic impedance, sympathetic nerve activity ( N=8 of 12), arterial pressure, and heart rate relative to supine conditions (all P
ISSN:1566-0702
1872-7484
DOI:10.1016/S1566-0702(02)00142-X