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Influenza A-Associated Encephalopathy with Bilateral Thalamic Necrosis in Japan

Two cases of acute encephalopathy in young children clearly showed evidence of influenza A virus infection and bilateral thalamic lesions. Influenza-associated encephalopathy with bilateral thalamic lesions has mostly been reported in Japan; it differs from Reye's syndrome in several respects....

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Published in:	Clinical infectious diseases 2000-08, Vol.31 (2), p.611-613
Main Authors:	Shinjoh, Masayoshi, Bamba, Masahiro, Jozaki, Keiji, Takahashi, Eisuke, Koinuma, Goro, Sugaya, Norio
Format:	Article
Language:	English
Subjects:	Biological and medical sciences Brain Diseases - diagnosis Brain Diseases - pathology Brain Diseases - virology Brief Reports Child, Preschool Encephalopathies Female H3N2 subtype influenza A virus Human viral diseases Humans Infant Infections Infectious diseases Influenza A virus Influenza A virus - isolation & purification Influenza, Human - complications Influenza, Human - virology Japan Lesions Male Medical sciences Necrosis Orthomyxoviridae Pediatrics Reye syndrome Thalamic Diseases - pathology Thalamic Diseases - virology Thalamus - pathology Thalamus - virology Viral diseases Viral diseases of the nervous system Viruses
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description	Two cases of acute encephalopathy in young children clearly showed evidence of influenza A virus infection and bilateral thalamic lesions. Influenza-associated encephalopathy with bilateral thalamic lesions has mostly been reported in Japan; it differs from Reye's syndrome in several respects. Other factors in addition to influenza virus infection may have contributed to the etiology of encephalopathy in our case patients.
doi_str_mv	10.1086/313978
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subjects	Biological and medical sciences Brain Diseases - diagnosis Brain Diseases - pathology Brain Diseases - virology Brief Reports Child, Preschool Encephalopathies Female H3N2 subtype influenza A virus Human viral diseases Humans Infant Infections Infectious diseases Influenza A virus Influenza A virus - isolation & purification Influenza, Human - complications Influenza, Human - virology Japan Lesions Male Medical sciences Necrosis Orthomyxoviridae Pediatrics Reye syndrome Thalamic Diseases - pathology Thalamic Diseases - virology Thalamus - pathology Thalamus - virology Viral diseases Viral diseases of the nervous system Viruses
title	Influenza A-Associated Encephalopathy with Bilateral Thalamic Necrosis in Japan
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