Influenza A-Associated Encephalopathy with Bilateral Thalamic Necrosis in Japan

Two cases of acute encephalopathy in young children clearly showed evidence of influenza A virus infection and bilateral thalamic lesions. Influenza-associated encephalopathy with bilateral thalamic lesions has mostly been reported in Japan; it differs from Reye's syndrome in several respects....

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Bibliographic Details
Published in:Clinical infectious diseases 2000-08, Vol.31 (2), p.611-613
Main Authors: Shinjoh, Masayoshi, Bamba, Masahiro, Jozaki, Keiji, Takahashi, Eisuke, Koinuma, Goro, Sugaya, Norio
Format: Article
Language:English
Subjects:
Biological and medical sciences
Brain Diseases - diagnosis
Brain Diseases - pathology
Brain Diseases - virology
Brief Reports
Child, Preschool
Encephalopathies
Female
H3N2 subtype influenza A virus
Human viral diseases
Humans
Infant
Infections
Infectious diseases
Influenza A virus
Influenza A virus - isolation & purification
Influenza, Human - complications
Influenza, Human - virology
Japan
Lesions
Male
Medical sciences
Necrosis
Orthomyxoviridae
Pediatrics
Reye syndrome
Thalamic Diseases - pathology
Thalamic Diseases - virology
Thalamus - pathology
Thalamus - virology
Viral diseases
Viral diseases of the nervous system
Viruses
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Description
Summary:Two cases of acute encephalopathy in young children clearly showed evidence of influenza A virus infection and bilateral thalamic lesions. Influenza-associated encephalopathy with bilateral thalamic lesions has mostly been reported in Japan; it differs from Reye's syndrome in several respects. Other factors in addition to influenza virus infection may have contributed to the etiology of encephalopathy in our case patients.
ISSN:1058-4838
1537-6591
DOI:10.1086/313978