Maximal functional capacity in patients with Chagas' cardiomyopathy without congestive heart failure

Background: Chagas' disease is a known dilated form of cardiomyopathy. However, a great number of patients, although showing electrocardiographic (ECG) well-recognized changes, maintain normal ventricular chamber dimensions and are asymptomatic. The aim of the present study was to objectively c...

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Bibliographic Details
Published in:Journal of cardiac failure 2000-09, Vol.6 (3), p.220-224
Main Authors: Mady, Charles, Ianni, Barbara Maria, Arteaga, Edmundo, Salemi, Vera Maria Cury, de Carvalho Frimm, Clovis
Format: Article
Language:English
Subjects:
Adult
cardiomyopathy
Case-Control Studies
Chagas Cardiomyopathy - physiopathology
Chagas' disease
Electrocardiography
Ergometry
Exercise Tolerance
Heart Conduction System - physiopathology
Heart Failure - physiopathology
Heart Rate
Humans
Male
maximal functional capacity
Oxygen Consumption
Severity of Illness Index
Spirometry
Systole
Ventricular Function, Left
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Summary:Background: Chagas' disease is a known dilated form of cardiomyopathy. However, a great number of patients, although showing electrocardiographic (ECG) well-recognized changes, maintain normal ventricular chamber dimensions and are asymptomatic. The aim of the present study was to objectively characterize functional capacity in asymptomatic patients with Chagas' disease and normal left ventricular function. Methods and Results: Eighteen asymptomatic male patients with Chagas' disease, aged 33 ± 6 years, were selected for the study. All showed ECG changes typical of the disease, as well as left ventricular fractional shortening (LVFS) greater than 0.30 on M-mode 2-dimensionally guided echocardiography. Twenty sedentary normal male patients, aged 29 ± 6 years, served as controls. Both groups were submitted to ergoespirometry testing for assessment of exercise functional capacity. Patients with Chagas' disease, when compared with controls, showed lower (P
ISSN:1071-9164
1532-8414
DOI:10.1054/jcaf.2000.8828