Brown tumor of the maxilla associated with primary hyperparathyroidism

Brown tumors represent the terminal stage of the remodeling processes during primary or secondary hyperparathyroidism. During the last three decades primary hyperparathyroidism has been recognized much more commonly and the increase has generally been attributed to the routine determination of calci...

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Bibliographic Details
Published in:Auris, nasus, larynx nasus, larynx, 2001-11, Vol.28 (4), p.369-372
Main Authors: Guney, Ercihan, Yigitbasi, O.Gazi, Bayram, Fahri, Ozer, Veli, Canoz, Özlem
Format: Article
Language:English
Subjects:
Adenoma - diagnosis
Adenoma - pathology
Alveolar Process - pathology
Bone Remodeling - physiology
Brown tumor
Diagnosis, Differential
Female
Humans
Hyperparathyroidism
Hyperparathyroidism - diagnosis
Hyperparathyroidism - pathology
Maxilla
Maxilla - pathology
Middle Aged
Osteitis Fibrosa Cystica - diagnosis
Osteitis Fibrosa Cystica - pathology
Osteoclasts - pathology
Parathyroid Neoplasms - diagnosis
Parathyroid Neoplasms - pathology
Tomography, X-Ray Computed
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Summary:Brown tumors represent the terminal stage of the remodeling processes during primary or secondary hyperparathyroidism. During the last three decades primary hyperparathyroidism has been recognized much more commonly and the increase has generally been attributed to the routine determination of calcium by new automated methods and the advent of new and more objective parathyroid hormone radioimmunoassay techniques. Early diagnosis and successful treatment of the disease have made clinical evidence of bone disease uncommon. While, the mandible is the most frequently involved bone in the head and neck region, maxillary involvement is extremely rare. A case of brown tumor on the maxilla associated with primary hyperparathyroidism is reported. This patient presented multiple skeletal lesions, which are uncommonly seen nowadays. The diagnosis was suggested by the clinical history and confirmed by biochemical, radiological and histopathological determinations. Excision of a parathyroid adenoma normalized the metabolic status. Excision of the maxillary mass led both histopathological confirmation of the disease and early masticator rehabilitation.
ISSN:0385-8146
1879-1476
DOI:10.1016/S0385-8146(01)00099-2