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Melanin and virulence in Cryptococcus neoformans
Melanin synthesis has been associated with virulence for the human pathogenic fungus Cryptococcus neoformans. Recent evidence indicates that C. neoformans cells synthesize melanin during infection and that this pigment protects the fungus against immune defense mechanisms.
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Published in: | Current Opinion in Microbiology 2000-08, Vol.3 (4), p.354-358 |
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container_title | Current Opinion in Microbiology |
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creator | Casadevall, Arturo Rosas, Angel L Nosanchuk, Joshua D |
description | Melanin synthesis has been associated with virulence for the human pathogenic fungus
Cryptococcus neoformans. Recent evidence indicates that
C. neoformans cells synthesize melanin during infection and that this pigment protects the fungus against immune defense mechanisms. |
doi_str_mv | 10.1016/S1369-5274(00)00103-X |
format | article |
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source | ScienceDirect Journals |
subjects | Animals Catecholamine Cryptococcosis - immunology Cryptococcosis - microbiology Cryptococcus neoformans Cryptococcus neoformans - metabolism Cryptococcus neoformans - pathogenicity Cryptococcus neoforms Fungi Humans Infection Melanin Melanins - metabolism Mice Pathogenesis Pathogenicity Pigment Virulence |
title | Melanin and virulence in Cryptococcus neoformans |
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