T wave alternans can decrease after coronary revascularization

Clinical observations and animal experiments indicate that T wave alternans (TWA) is associated with an increased propensity for ventricular fibrillation, and thus it may be considered as a noninvasive marker of life-threatening ventricular arrhythmias. There is substantial evidence indicating that...

Full description

Saved in:
Bibliographic Details
Published in:Angiology 2000-08, Vol.51 (8), p.677-687
Main Authors: MUSTAFA KEMAL BATUR, OTO, A, IDER, Z, AKSÖYEK, S, KABAKCI, G, OVÜNC, K, TOKGÖZOGLU, L, OZMEN, F
Format: Article
Language:English
Subjects:
Angioplasty, Balloon, Coronary - adverse effects
Biological and medical sciences
Cardiology. Vascular system
Coronary heart disease
Electrocardiography
Female
Fourier Analysis
Heart
Heart Rate
Humans
Male
Medical sciences
Middle Aged
Myocardial Ischemia - complications
Myocardial Ischemia - physiopathology
Myocardial Ischemia - therapy
Prognosis
Stents
Ventricular Fibrillation - etiology
Ventricular Fibrillation - physiopathology
Ventricular Fibrillation - prevention & control
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Clinical observations and animal experiments indicate that T wave alternans (TWA) is associated with an increased propensity for ventricular fibrillation, and thus it may be considered as a noninvasive marker of life-threatening ventricular arrhythmias. There is substantial evidence indicating that TWA is an intrinsic property of ischemic myocardium. This study was performed to determine the role of percutaneous transluminal coronary angioplasty (PTCA)-induced myocardial ischemia in the development of TWA and the effects of revascularization. The authors recorded bipolar X, Y, and Z leads of 111 consecutive patients (mean age: 56 years) undergoing PTCA before, during, and 24 hours after the procedure. T wave alternans signal was calculated in 97 patients (43 left anterior descending, 26 right coronary artery, and 28 circumflex or major obtuse margin branch) by fast Fourier transformation technique after signal processing. Twenty-four hours after the procedure, the mean and peak X, Y, and Z values for TWA had all been significantly reduced from baseline and during balloon inflation (p
ISSN:0003-3197
1940-1574