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Role of ionic transport in regulation of hemoglobin affinity for oxygen in diabetes mellitus
The rate of Na(+)/H(+) exchange is increased by 24%, activities of Ca-dependent K+ channels is increased by 13%, and activity of erythrocyte Ca(2+)-ATPase decreased by 17% in patients with diabetes mellitus concomitant with essential hypertension in comparison with patients with essential hypertensi...
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Published in: | Bulletin of experimental biology and medicine 2002-04, Vol.133 (4), p.396-398 |
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Main Authors: | , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that cite this one |
Online Access: | Get full text |
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Summary: | The rate of Na(+)/H(+) exchange is increased by 24%, activities of Ca-dependent K+ channels is increased by 13%, and activity of erythrocyte Ca(2+)-ATPase decreased by 17% in patients with diabetes mellitus concomitant with essential hypertension in comparison with patients with essential hypertension without disorders of carbohydrate metabolism. Changes in activity of Na(+)/H(+) exchange, Ca-dependent K(+) channels, and erythrocyte Ca(2+)-ATPase and increased oxygen affinity of hemoglobin are due to increased glucose concentration in the plasma and are leveled by olifen. |
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ISSN: | 0007-4888 1573-8221 |
DOI: | 10.1023/A:1016266525531 |