Human fascioliasis

Fasciola hepatica, a zoonotic liver fluke, can also cause disease in humans. Common symptoms are epigastric pain, upper abdominal pain and malaise. Fever and arthralgia are common in acute fascioliasis. Eosinophilia is the predominant laboratory finding, especially in patients with the acute form of...

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Bibliographic Details
Published in:Clinical microbiology and infection 2004-05, Vol.10 (5), p.385-387
Main Authors: Saba, R., Korkmaz, M., Inan, D., Mamikoğlu, L., Turhan, Ö., Günseren, F., Çevikol, C., Kabaalioğlu, A.
Format: Article
Language:English
Subjects:
Adult
Aged
Albendazole - therapeutic use
Animals
Antibodies, Helminth - analysis
Antiplatyhelmintic Agents - therapeutic use
Benzimidazoles - therapeutic use
Diagnosis
Fasciola hepatica
Fasciola hepatica - drug effects
Fasciola hepatica - immunology
fascioliasis
Fascioliasis - diagnosis
Fascioliasis - drug therapy
Fascioliasis - parasitology
Female
Humans
Male
Middle Aged
Praziquantel - analogs & derivatives
Praziquantel - therapeutic use
treatment
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Summary:Fasciola hepatica, a zoonotic liver fluke, can also cause disease in humans. Common symptoms are epigastric pain, upper abdominal pain and malaise. Fever and arthralgia are common in acute fascioliasis. Eosinophilia is the predominant laboratory finding, especially in patients with the acute form of the disease. Diagnosis and treatment is not easy, as physicians rarely encounter this disease, and effective drugs are not available in many countries. Human fascioliasis may be underestimated. Patients with eosinophilia and abdominal pain should be evaluated for F. hepatica infestation by parasitological, radiological and serological tests.
ISSN:1198-743X
1469-0691
DOI:10.1111/j.1469-0691.2004.00820.x