Management of T1–T2 glottic carcinomas

T1–T2 glottic carcinomas may be treated with conservative surgery or radiotherapy. The goals of treatment are cure and laryngeal voice preservation. The aim of the current study was to review the pertinent literature and discuss the optimal management of early‐stage laryngeal carcinoma. Literature r...

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Bibliographic Details
Published in:Cancer 2004-05, Vol.100 (9), p.1786-1792
Main Authors: Mendenhall, William M., Werning, John W., Hinerman, Russell W., Amdur, Robert J., Villaret, Douglas B.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Biopsy, Needle
carcinoma
Combined Modality Therapy
Female
Glottis - pathology
head and neck neoplasm
Humans
Laryngeal Neoplasms - mortality
Laryngeal Neoplasms - pathology
Laryngeal Neoplasms - therapy
laryngectomy
Laryngectomy - methods
larynx
Laser Therapy - methods
Male
Medical sciences
Neoplasm Staging
Prognosis
radiotherapy
Radiotherapy Dosage
Radiotherapy, Adjuvant
Randomized Controlled Trials as Topic
Risk Assessment
Survival Analysis
Treatment Outcome
Tumors
voice
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Summary:T1–T2 glottic carcinomas may be treated with conservative surgery or radiotherapy. The goals of treatment are cure and laryngeal voice preservation. The aim of the current study was to review the pertinent literature and discuss the optimal management of early‐stage laryngeal carcinoma. Literature review indicated that the local control, laryngeal preservation, and survival rates of patients were similar after transoral laser resection, open partial laryngectomy, and radiotherapy. Voice quality depended on the extent of resection for patients undergoing surgery; results for patients undergoing laser resection for limited lesions were comparable to the corresponding results for patients receiving radiotherapy, whereas open partial laryngectomy yielded poorer results. Costs were similar for laser resection and radiotherapy, but open partial laryngectomy was more expensive. Patients with well defined lesions suitable for transoral laser excision with a good functional outcome were treated with either laser or radiotherapy. The remaining patients were optimally treated with radiotherapy. Open partial laryngectomy was reserved for patients with locally recurrent tumors. Cancer 2004. © 2004 American Cancer Society. Well defined lesions suitable for transoral laser excision with a good functional outcome were treated with either laser or radiotherapy. Remaining T1–T2 tumors were optimally treated with radiotherapy. Open partial laryngectomy was reserved for salvage treatment of patients with locally recurrent tumors.
ISSN:0008-543X
1097-0142
DOI:10.1002/cncr.20181