An update on corneal hydration control

An account is provided of developments in our understanding of the mechanism of corneal hydration control, particularly as regards the possibility of an active system for its regulation. Emphasis is given to issues that are contentious, such as the role of bicarbonate in the endothelial pump and the...

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Bibliographic Details
Published in:Experimental Eye Research 2004-03, Vol.78 (3), p.537-541
Main Authors: Fischbarg, Jorge, Maurice, David M.
Format: Article
Language:English
Subjects:
Anion Transport Proteins - physiology
bicarbonate
Bicarbonates - metabolism
Body Water - metabolism
Cell Membrane Permeability - physiology
Cornea - metabolism
Endothelium, Corneal - metabolism
Epithelium, Corneal - metabolism
fluid pump
Humans
light scattering
osmosis
swelling
transport
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Summary:An account is provided of developments in our understanding of the mechanism of corneal hydration control, particularly as regards the possibility of an active system for its regulation. Emphasis is given to issues that are contentious, such as the role of bicarbonate in the endothelial pump and the significance of water channels in both corneal limiting cell layers.
ISSN:0014-4835
1096-0007
DOI:10.1016/j.exer.2003.09.010