Aneurysmal sub-arachnoid haemorrhage in patients with Noonan syndrome: a report of two cases and review of neurovascular presentations in this syndrome

To date, intracranial aneurysms have been reported in two patients with Noonan syndrome. We report two unrelated patients with Noonan syndrome who presented with sub-arachnoid haemorrhage secondary to intracranial aneurysms. These cases are discussed and other cerebrovascular abnormalities that have...

Full description

Saved in:
Bibliographic Details
Published in:Neuroradiology 2004-04, Vol.46 (4), p.301-305
Main Authors: DINEEN, R. A, LENTHALL, R. K
Format: Article
Language:English
Subjects:
Adult
Aneurysms
Biological and medical sciences
Cerebral Angiography
Female
Humans
Intracranial Aneurysm - complications
Intracranial Aneurysm - etiology
Investigative techniques, diagnostic techniques (general aspects)
Medical sciences
Nervous system
Neurology
Noonan Syndrome - complications
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Radiology
Subarachnoid Hemorrhage - diagnostic imaging
Subarachnoid Hemorrhage - etiology
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To date, intracranial aneurysms have been reported in two patients with Noonan syndrome. We report two unrelated patients with Noonan syndrome who presented with sub-arachnoid haemorrhage secondary to intracranial aneurysms. These cases are discussed and other cerebrovascular abnormalities that have been described in association with Noonan syndrome are reviewed. Ultrastructural and genetic factors contributing to these associations are considered.
ISSN:0028-3940
1432-1920
DOI:10.1007/s00234-004-1185-3