Novel CCR1 antagonists with improved metabolic stability

The synthesis, biological activity, and pharmacokinetic profile of novel CCR1 antagonists are described.

Bibliographic Details

Published in:	Bioorganic & medicinal chemistry letters 2004-05, Vol.14 (9), p.2175-2179
Main Authors:	BROWN, Matthew F, AVERY, Mike, LIRA, Paul D, LILLIE, Brett M, LUNDQUIST, Greg D, MAIRS, Erin N, MCELROY, Eric B, MCGLYNN, Molly A, PARADIS, Timothy J, POSS, Christopher S, ROSSULEK, Michelle I, SHEPARD, Richard M, BRISSETTE, William H, SIMS, Jeff, STRELEVITZ, Timothy J, TRUESDELL, Susan, TYLASKA, Laurie A, YOON, Kwansik, DEYE ZHENG, CHANG, J. H, COLIZZA, Kevin, CONKLYN, Maryrose, DIRICO, Amy P, GLADUE, Ronald P, KATH, John C, KRUEGER, Suzanne S
Format:	Article
Language:	English
Subjects:	Animals Biological and medical sciences Dogs Haplorhini Medical sciences Miscellaneous Pharmacokinetics Pharmacology. Drug treatments Receptors, CCR1 Receptors, Chemokine - antagonists & inhibitors
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