Head-to-Head Comparison of Fundamental, Tissue Harmonic and Contrast Harmonic Imaging With or Without an Air-Filled Contrast Agent, Levovist, for Endocardial Border Delineation in Patients With Poor Quality Images

Recent developments in tissue harmonic imaging and intravenous contrast agents have enhanced left ventricular endocardial border delineation (EBD). In a total of 48 patients with poor quality images, apical 4- and 2-chamber views were obtained with fundamental, tissue harmonic and contrast harmonic...

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Bibliographic Details
Published in:Circulation Journal 2002, Vol.66(5), pp.494-498
Main Authors: Yoshitani, Hidetoshi, Takeuchi, Masaaki, Hirose, Makoto, Miyazaki, Chinami, Otani, Shinichiro, Sakamoto, Kazuo, Yoshikawa, Junichi
Format: Article
Language:English
Subjects:
Aged
Biological and medical sciences
Cardiovascular system
Contrast agent
Contrast Media
Echocardiography
Endocardium - diagnostic imaging
Female
Harmonic imaging
Humans
Investigative techniques, diagnostic techniques (general aspects)
Levovist
LV opacification
Male
Medical sciences
Middle Aged
Polysaccharides
Ultrasonic investigative techniques
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Summary:Recent developments in tissue harmonic imaging and intravenous contrast agents have enhanced left ventricular endocardial border delineation (EBD). In a total of 48 patients with poor quality images, apical 4- and 2-chamber views were obtained with fundamental, tissue harmonic and contrast harmonic imaging with or without intravenous Levovist, an air-filled contrast agent. The left ventricle (LV) was divided into 12 segments, and the EBD of each segment was scored: (1) not visible, (2) barely visible, (3) well delineated. The EBD index (EBDI), defined as the sum of the endocardial scores divided by 12 was obtained for each patient. Of a total of 576 LV segments, 231 were scored as 1 by fundamental imaging and that number decreased to 125 segments by tissue harmonic imaging and 116 segments by fundamental imaging with Levovist. The number of segments scored as 1 decreased to 38 segments by tissue harmonic imaging with Levovist, and to 29 segments by contrast harmonic imaging with Levovist. The EBDI by fundamental imaging was 1.85±0.29, which improved significantly with the addition of Levovist (2.10±0.36, p
ISSN:1346-9843
1347-4820
DOI:10.1253/circj.66.494