Malignant Eccrine Acrospiroma with Metastasis to the Parotid

Malignant eccrine acrospiromas are rare. Clinically, they resemble other cutaneous lesions. A high index of suspicion must be maintained in cases of histologically benign eccrine acrospiromas for three reasons: (1) malignant transformation can occur, (2) the presence of both benign and malignant tis...

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Bibliographic Details
Published in:Ear, nose, & throat journal nose, & throat journal, 2002-05, Vol.81 (5), p.352-355
Main Authors: Holden, Bridget, Colome-Grimmer, Maria, Savage, Clare, Stierman, Karen, Pou, Anna M.
Format: Article
Language:English
Subjects:
Acrospiroma - pathology
Acrospiroma - therapy
Aged
Aged, 80 and over
Biological and medical sciences
Dermatology
Humans
Male
Medical sciences
Otorhinolaryngology. Stomatology
Parotid Neoplasms - secondary
Parotid Neoplasms - therapy
Sweat Gland Neoplasms - pathology
Sweat Gland Neoplasms - therapy
Tumors
Tumors of the skin and soft tissue. Premalignant lesions
Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology
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Summary:Malignant eccrine acrospiromas are rare. Clinically, they resemble other cutaneous lesions. A high index of suspicion must be maintained in cases of histologically benign eccrine acrospiromas for three reasons: (1) malignant transformation can occur, (2) the presence of both benign and malignant tissue can lead to a false-negative diagnosis if only the benign component is obtained in the biopsy specimen, and (3) benign-appearing tumors can recur locally or metastasize. The primary treatment is wide local excision with or without lymph node dissection. The efficacy of adjuvant chemotherapy and radiation therapy requires further investigation. We describe a case of malignant eccrine acrospiroma in an 80-year-old man, and we review the literature on this tumor, with emphasis on the differential diagnosis.
ISSN:0145-5613
1942-7522
DOI:10.1177/014556130208100515