Outcomes of patients with chronic renal insufficiency in the Bypass Angioplasty Revascularization Investigation

Although severe chronic kidney disease (CKD) is an independent predictor of mortality among patients with coronary artery disease, the impact of mild CKD on morbidity and mortality has not been fully defined. Morbidity and mortality for the 3608 patients with multivessel coronary artery disease enro...

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Bibliographic Details
Published in:Circulation (New York, N.Y.) N.Y.), 2002-05, Vol.105 (19), p.2253-2258
Main Authors: SZCZECH, L. A, BEST, P. J, WHITLOW, P. J, DETRE, K. M, HOLMES, D, CROWLEY, E, BROOKS, M. M, BERGER, P. B, BITTNER, V, GERSH, B. J, JONES, R, CALIFF, R. M, TING, H. H
Format: Article
Language:English
Subjects:
Angina Pectoris - etiology
Angioplasty, Balloon, Coronary - adverse effects
Biological and medical sciences
Cardiology. Vascular system
Coronary Artery Bypass - adverse effects
Coronary Artery Disease - complications
Coronary Artery Disease - surgery
Coronary heart disease
Creatinine - blood
Diabetes Complications
Female
Follow-Up Studies
Heart
Hospitalization - statistics & numerical data
Humans
Kidney Failure, Chronic - blood
Kidney Failure, Chronic - complications
Male
Medical sciences
Middle Aged
Myocardial Revascularization
Postoperative Complications
Proportional Hazards Models
Recurrence
Reoperation - statistics & numerical data
Risk
Risk Assessment
Risk Factors
Survival Rate
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Summary:Although severe chronic kidney disease (CKD) is an independent predictor of mortality among patients with coronary artery disease, the impact of mild CKD on morbidity and mortality has not been fully defined. Morbidity and mortality for the 3608 patients with multivessel coronary artery disease enrolled in the Bypass Angioplasty Revascularization Investigation randomized trial and registry were compared on the basis of the presence and absence of CKD, defined as a preprocedure serum creatinine level of >1.5 mg/dL. Seventy-six patients had CKD. Patients with renal insufficiency were older and more likely to have a history of diabetes, hypertension, and other comorbidities. Among patients undergoing PTCA, patients with CKD had a greater frequency of in-hospital death and cardiogenic shock (P
ISSN:0009-7322
1524-4539
DOI:10.1161/01.CIR.0000016051.33225.33