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Quality of life and symptomatic outcome three to five years after laparoscopic Toupet fundoplication in gastroesophageal reflux disease patients with impaired esophageal motility

Background: Many centers practice a tailored approach to laparoscopic antireflux surgery in attempt to prevent postoperative side effects in gastroesophageal reflux disease (GERD) patients with an impaired esophageal motility. As a result of controversial findings reported in literature no worldwide...

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Bibliographic Details
Published in:The American journal of surgery 2002-02, Vol.183 (2), p.110-116
Main Authors: Granderath, Frank Alexander, Kamolz, Thomas, Schweiger, Ursula Maria, Pasiut, Martin, Wykypiel, Heinz, Pointner, Rudolph
Format: Article
Language:English
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Summary:Background: Many centers practice a tailored approach to laparoscopic antireflux surgery in attempt to prevent postoperative side effects in gastroesophageal reflux disease (GERD) patients with an impaired esophageal motility. As a result of controversial findings reported in literature no worldwide accepted consensus exists regarding the appropriate indication for this tailored approach. The aim of this prospective study was to evaluate quality of life and symptomatic outcome in selected patients for a follow-up of 3 to 5 years. Methods: A total of 155 patients with esophageal dismotility underwent laparoscopic Toupet fundoplication (LTF). Basic requirements for surgery included in all patients a detailed evaluation of symptoms and quality of life (Gastrointestinal Quality of Life Index [GIQLI]), esophagogastroduodenoscopy, 24-hour pH monitoring, and esophageal manometry. Patients were evaluated 6 weeks, 3 months, 1 year, and 3 to 5 years after LTF. Results: GERD-related symptoms such as heartburn, regurgitation, dysphagia, or chest pain showed a significant improvement ( P
ISSN:0002-9610
1879-1883
DOI:10.1016/S0002-9610(01)00868-6